Cargando…
Demographic and Psychosocial factors associated with Hair Cortisol Concentrations in Preschool Children
BACKGROUND: Early life stress has enduring effects on physical and mental health. Hair cortisol concentrations (HCC) reflect exposures to contextual stressors in early life, but are understudied in preschool children. METHODS: Hair samples from children (N=693) during clinic visits (CV) scheduled at...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196501/ https://www.ncbi.nlm.nih.gov/pubmed/31791042 http://dx.doi.org/10.1038/s41390-019-0691-2 |
_version_ | 1783528735880773632 |
---|---|
author | Anand, Kanwaljeet J. S. Rovnaghi, Cynthia R. Rigdon, Joseph Qin, FeiFei Tembulkar, Sahil Murphy, Laura E. Barr, Donald A. Gotlib, Ian H. Tylavsky, Frances A. |
author_facet | Anand, Kanwaljeet J. S. Rovnaghi, Cynthia R. Rigdon, Joseph Qin, FeiFei Tembulkar, Sahil Murphy, Laura E. Barr, Donald A. Gotlib, Ian H. Tylavsky, Frances A. |
author_sort | Anand, Kanwaljeet J. S. |
collection | PubMed |
description | BACKGROUND: Early life stress has enduring effects on physical and mental health. Hair cortisol concentrations (HCC) reflect exposures to contextual stressors in early life, but are understudied in preschool children. METHODS: Hair samples from children (N=693) during clinic visits (CV) scheduled at 1–4 years (CV1-CV4) were measured using validated assay methods for HCC. RESULTS: HCC were highest at CV1 and decreased at CV2-CV4, with no sex differences. Black children had higher HCC than White/other children; these differences persisted even after adjusting for socioeconomic factors. Bivariable analyses showed significant effects on HCC for Black race, with specific demographic and psychosocial factors at different ages. Multivariable analyses showed that higher HCC at CV1 were associated with Black race and male sex; at CV2 with Black race, lower maternal self-esteem, socioeconomic adversity, and the child’s risk for developmental delay; at CV3 with Black race; at CV4 with maternal depression and the child’s prior HCC values. CONCLUSIONS: HCC were higher in Black children than White/other races; differences were related to maternal factors, socioeconomic adversity, and the child’s risk for developmental delay. Public health measures to reduce disparities between Blacks and other races must also consider the long-term effects of chronic stress in early life. |
format | Online Article Text |
id | pubmed-7196501 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
record_format | MEDLINE/PubMed |
spelling | pubmed-71965012020-06-02 Demographic and Psychosocial factors associated with Hair Cortisol Concentrations in Preschool Children Anand, Kanwaljeet J. S. Rovnaghi, Cynthia R. Rigdon, Joseph Qin, FeiFei Tembulkar, Sahil Murphy, Laura E. Barr, Donald A. Gotlib, Ian H. Tylavsky, Frances A. Pediatr Res Article BACKGROUND: Early life stress has enduring effects on physical and mental health. Hair cortisol concentrations (HCC) reflect exposures to contextual stressors in early life, but are understudied in preschool children. METHODS: Hair samples from children (N=693) during clinic visits (CV) scheduled at 1–4 years (CV1-CV4) were measured using validated assay methods for HCC. RESULTS: HCC were highest at CV1 and decreased at CV2-CV4, with no sex differences. Black children had higher HCC than White/other children; these differences persisted even after adjusting for socioeconomic factors. Bivariable analyses showed significant effects on HCC for Black race, with specific demographic and psychosocial factors at different ages. Multivariable analyses showed that higher HCC at CV1 were associated with Black race and male sex; at CV2 with Black race, lower maternal self-esteem, socioeconomic adversity, and the child’s risk for developmental delay; at CV3 with Black race; at CV4 with maternal depression and the child’s prior HCC values. CONCLUSIONS: HCC were higher in Black children than White/other races; differences were related to maternal factors, socioeconomic adversity, and the child’s risk for developmental delay. Public health measures to reduce disparities between Blacks and other races must also consider the long-term effects of chronic stress in early life. 2019-12-02 2020-05 /pmc/articles/PMC7196501/ /pubmed/31791042 http://dx.doi.org/10.1038/s41390-019-0691-2 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms |
spellingShingle | Article Anand, Kanwaljeet J. S. Rovnaghi, Cynthia R. Rigdon, Joseph Qin, FeiFei Tembulkar, Sahil Murphy, Laura E. Barr, Donald A. Gotlib, Ian H. Tylavsky, Frances A. Demographic and Psychosocial factors associated with Hair Cortisol Concentrations in Preschool Children |
title | Demographic and Psychosocial factors associated with Hair Cortisol Concentrations in Preschool Children |
title_full | Demographic and Psychosocial factors associated with Hair Cortisol Concentrations in Preschool Children |
title_fullStr | Demographic and Psychosocial factors associated with Hair Cortisol Concentrations in Preschool Children |
title_full_unstemmed | Demographic and Psychosocial factors associated with Hair Cortisol Concentrations in Preschool Children |
title_short | Demographic and Psychosocial factors associated with Hair Cortisol Concentrations in Preschool Children |
title_sort | demographic and psychosocial factors associated with hair cortisol concentrations in preschool children |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196501/ https://www.ncbi.nlm.nih.gov/pubmed/31791042 http://dx.doi.org/10.1038/s41390-019-0691-2 |
work_keys_str_mv | AT anandkanwaljeetjs demographicandpsychosocialfactorsassociatedwithhaircortisolconcentrationsinpreschoolchildren AT rovnaghicynthiar demographicandpsychosocialfactorsassociatedwithhaircortisolconcentrationsinpreschoolchildren AT rigdonjoseph demographicandpsychosocialfactorsassociatedwithhaircortisolconcentrationsinpreschoolchildren AT qinfeifei demographicandpsychosocialfactorsassociatedwithhaircortisolconcentrationsinpreschoolchildren AT tembulkarsahil demographicandpsychosocialfactorsassociatedwithhaircortisolconcentrationsinpreschoolchildren AT murphylaurae demographicandpsychosocialfactorsassociatedwithhaircortisolconcentrationsinpreschoolchildren AT barrdonalda demographicandpsychosocialfactorsassociatedwithhaircortisolconcentrationsinpreschoolchildren AT gotlibianh demographicandpsychosocialfactorsassociatedwithhaircortisolconcentrationsinpreschoolchildren AT tylavskyfrancesa demographicandpsychosocialfactorsassociatedwithhaircortisolconcentrationsinpreschoolchildren |