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The Secretome Profiling of a Pediatric Airway Epithelium Infected with hRSV Identified Aberrant Apical/Basolateral Trafficking and Novel Immune Modulating (CXCL6, CXCL16, CSF3) and Antiviral (CEACAM1) Proteins

The respiratory epithelium comprises polarized cells at the interface between the environment and airway tissues. Polarized apical and basolateral protein secretions are a feature of airway epithelium homeostasis. Human respiratory syncytial virus (hRSV) is a major human pathogen that primarily targ...

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Detalles Bibliográficos
Autores principales: Touzelet, Olivier, Broadbent, Lindsay, Armstrong, Stuart D., Aljabr, Waleed, Cloutman-Green, Elaine, Power, Ultan F., Hiscox, Julian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196588/
https://www.ncbi.nlm.nih.gov/pubmed/32075873
http://dx.doi.org/10.1074/mcp.RA119.001546