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NAD(+) biosynthesis in bacteria is controlled by global carbon/nitrogen levels via PII signaling

NAD(+) is a central metabolite participating in core metabolic redox reactions. The prokaryotic NAD synthetase enzyme NadE catalyzes the last step of NAD(+) biosynthesis, converting nicotinic acid adenine dinucleotide (NaAD) to NAD(+). Some members of the NadE family use l-glutamine as a nitrogen do...

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Detalles Bibliográficos
Autores principales: Santos, Adrian Richard Schenberger, Gerhardt, Edileusa Cristina Marques, Parize, Erick, Pedrosa, Fabio Oliveira, Steffens, Maria Berenice Reynaud, Chubatsu, Leda Satie, Souza, Emanuel Maltempi, Passaglia, Luciane Maria Pereira, Sant'Anna, Fernando Hayashi, de Souza, Gustavo Antônio, Huergo, Luciano Fernandes, Forchhammer, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196632/
https://www.ncbi.nlm.nih.gov/pubmed/32179648
http://dx.doi.org/10.1074/jbc.RA120.012793

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