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Delineating an extracellular redox-sensitive module in T-type Ca(2+) channels

T-type (Cav3) Ca(2+) channels are important regulators of excitability and rhythmic activity of excitable cells. Among other voltage-gated Ca(2+) channels, Cav3 channels are uniquely sensitive to oxidation and zinc. Using recombinant protein expression in HEK293 cells, patch clamp electrophysiology,...

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Detalles Bibliográficos
Autores principales:	Huang, Dongyang, Shi, Sai, Liang, Ce, Zhang, Xiaoyu, Du, Xiaona, An, Hailong, Peers, Chris, Zhang, Hailin, Gamper, Nikita
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196644/ https://www.ncbi.nlm.nih.gov/pubmed/32188693 http://dx.doi.org/10.1074/jbc.RA120.012668

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