A comparative analysis of gene expression induced by the embryo in the caprine endometrium

Transcriptomics is an established powerful tool to identify potential mRNAs and ncRNAs (non‐coding RNAs) for endometrial receptivity. In this study, the goat endometrium at estrus day 5 (ED5) and estrus day 15 (ED15) were selected to systematically analyse the differential expressed genes (DEGs) wha...

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Autores principales: Liu, Xiaorui, Zhang, Lei, Han, Jincheng, Yang, Lichun, Cui, Jiuzeng, Che, Sicheng, Cao, Binyun, Song, Yuxuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196676/
https://www.ncbi.nlm.nih.gov/pubmed/31782264
http://dx.doi.org/10.1002/vms3.221
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author Liu, Xiaorui
Zhang, Lei
Han, Jincheng
Yang, Lichun
Cui, Jiuzeng
Che, Sicheng
Cao, Binyun
Song, Yuxuan
author_facet Liu, Xiaorui
Zhang, Lei
Han, Jincheng
Yang, Lichun
Cui, Jiuzeng
Che, Sicheng
Cao, Binyun
Song, Yuxuan
author_sort Liu, Xiaorui
collection PubMed
description Transcriptomics is an established powerful tool to identify potential mRNAs and ncRNAs (non‐coding RNAs) for endometrial receptivity. In this study, the goat endometrium at estrus day 5 (ED5) and estrus day 15 (ED15) were selected to systematically analyse the differential expressed genes (DEGs) what were induced by the embryo. There were 1,847 genes which were significantly differential expressed in endometrium induced by the embryo at ED5, and 1,346 at ED15 (p‐value < .05). Secreted phosphoprotein 1 (SPP) was the responsive genes for embryo in the goat endometrium during estrus cycle, neurotensis (NTS) and pleiotrophin (PTN) were the responsive genes for embryo in the goat endometrium at ED5, Testin (TES) and Phosphate and Tension Homology Deleted on Chromsome ten (PTEN) at ED15. Furthermore, Gene Ontology (GO) and Kyoto Encyclopedia of Genes (KEGG) analysis revealed cytoplasm and Endocytosis were indispensable for the endometrium development in dairy goat. In a word, this resulting view of the transcriptome greatly uncovered the global trends in mRNAs expression induced by the embryo in the endometrium of dairy goats.
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spelling pubmed-71966762020-05-05 A comparative analysis of gene expression induced by the embryo in the caprine endometrium Liu, Xiaorui Zhang, Lei Han, Jincheng Yang, Lichun Cui, Jiuzeng Che, Sicheng Cao, Binyun Song, Yuxuan Vet Med Sci Original Articles Transcriptomics is an established powerful tool to identify potential mRNAs and ncRNAs (non‐coding RNAs) for endometrial receptivity. In this study, the goat endometrium at estrus day 5 (ED5) and estrus day 15 (ED15) were selected to systematically analyse the differential expressed genes (DEGs) what were induced by the embryo. There were 1,847 genes which were significantly differential expressed in endometrium induced by the embryo at ED5, and 1,346 at ED15 (p‐value < .05). Secreted phosphoprotein 1 (SPP) was the responsive genes for embryo in the goat endometrium during estrus cycle, neurotensis (NTS) and pleiotrophin (PTN) were the responsive genes for embryo in the goat endometrium at ED5, Testin (TES) and Phosphate and Tension Homology Deleted on Chromsome ten (PTEN) at ED15. Furthermore, Gene Ontology (GO) and Kyoto Encyclopedia of Genes (KEGG) analysis revealed cytoplasm and Endocytosis were indispensable for the endometrium development in dairy goat. In a word, this resulting view of the transcriptome greatly uncovered the global trends in mRNAs expression induced by the embryo in the endometrium of dairy goats. John Wiley and Sons Inc. 2019-11-28 /pmc/articles/PMC7196676/ /pubmed/31782264 http://dx.doi.org/10.1002/vms3.221 Text en © 2019 The Authors. Veterinary Medicine and Science Published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Liu, Xiaorui
Zhang, Lei
Han, Jincheng
Yang, Lichun
Cui, Jiuzeng
Che, Sicheng
Cao, Binyun
Song, Yuxuan
A comparative analysis of gene expression induced by the embryo in the caprine endometrium
title A comparative analysis of gene expression induced by the embryo in the caprine endometrium
title_full A comparative analysis of gene expression induced by the embryo in the caprine endometrium
title_fullStr A comparative analysis of gene expression induced by the embryo in the caprine endometrium
title_full_unstemmed A comparative analysis of gene expression induced by the embryo in the caprine endometrium
title_short A comparative analysis of gene expression induced by the embryo in the caprine endometrium
title_sort comparative analysis of gene expression induced by the embryo in the caprine endometrium
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196676/
https://www.ncbi.nlm.nih.gov/pubmed/31782264
http://dx.doi.org/10.1002/vms3.221
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