Cargando…

Local and regional anaesthesia in dogs and cats: Overview of concepts and drugs (Part 1)

Pain management in veterinary patients is a crucial component of appropriate patient care. Multimodal analgesia that includes both systemically and locally/regionally administered drugs is generally the most effective approach to providing pain relief. Local anaesthetic drugs used in local and regio...

Descripción completa

Detalles Bibliográficos
Autores principales: Grubb, Tamara, Lobprise, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196681/
https://www.ncbi.nlm.nih.gov/pubmed/31965742
http://dx.doi.org/10.1002/vms3.219
_version_ 1783528759809277952
author Grubb, Tamara
Lobprise, Heidi
author_facet Grubb, Tamara
Lobprise, Heidi
author_sort Grubb, Tamara
collection PubMed
description Pain management in veterinary patients is a crucial component of appropriate patient care. Multimodal analgesia that includes both systemically and locally/regionally administered drugs is generally the most effective approach to providing pain relief. Local anaesthetic drugs used in local and regional blockade are unique in that they can completely block the transmission of pain (in conscious patients) or nociceptive (in anaesthetized patients) signals, thereby providing profound analgesia. In addition, local and regional administration of drugs, when compared with systemic bolus administration, generally results in a lower incidence of dose‐related adverse effects. Due to the potential to provide profound analgesia and the high safety margin (when used correctly) of this drug class, local anaesthetics are recommended as part of the analgesic protocol in the majority of patients undergoing surgical procedures or suffering traumatic injuries. This manuscript, Part 1 of a two‐part instalment, emphasizes the importance of using local and regional anaesthesia as a component of multimodal analgesia, provides a review of the basic pharmacokinetics/pharmacodynamics of local anaesthetic drugs in general, lists information on commonly used local anaesthetic drugs for local and regional blockade in dogs and cats, and briefly introduces the novel liposome‐encapsulated bupivacaine (NOCITA®). Part 2 is a review of local and regional anaesthetic techniques used in dogs and cats (Grubb & Lobprise, 2020).
format Online
Article
Text
id pubmed-7196681
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-71966812020-05-05 Local and regional anaesthesia in dogs and cats: Overview of concepts and drugs (Part 1) Grubb, Tamara Lobprise, Heidi Vet Med Sci Reviews Pain management in veterinary patients is a crucial component of appropriate patient care. Multimodal analgesia that includes both systemically and locally/regionally administered drugs is generally the most effective approach to providing pain relief. Local anaesthetic drugs used in local and regional blockade are unique in that they can completely block the transmission of pain (in conscious patients) or nociceptive (in anaesthetized patients) signals, thereby providing profound analgesia. In addition, local and regional administration of drugs, when compared with systemic bolus administration, generally results in a lower incidence of dose‐related adverse effects. Due to the potential to provide profound analgesia and the high safety margin (when used correctly) of this drug class, local anaesthetics are recommended as part of the analgesic protocol in the majority of patients undergoing surgical procedures or suffering traumatic injuries. This manuscript, Part 1 of a two‐part instalment, emphasizes the importance of using local and regional anaesthesia as a component of multimodal analgesia, provides a review of the basic pharmacokinetics/pharmacodynamics of local anaesthetic drugs in general, lists information on commonly used local anaesthetic drugs for local and regional blockade in dogs and cats, and briefly introduces the novel liposome‐encapsulated bupivacaine (NOCITA®). Part 2 is a review of local and regional anaesthetic techniques used in dogs and cats (Grubb & Lobprise, 2020). John Wiley and Sons Inc. 2020-01-21 /pmc/articles/PMC7196681/ /pubmed/31965742 http://dx.doi.org/10.1002/vms3.219 Text en © 2020 The Authors. Veterinary Medicine and Science Published by John Wiley & Sons Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Grubb, Tamara
Lobprise, Heidi
Local and regional anaesthesia in dogs and cats: Overview of concepts and drugs (Part 1)
title Local and regional anaesthesia in dogs and cats: Overview of concepts and drugs (Part 1)
title_full Local and regional anaesthesia in dogs and cats: Overview of concepts and drugs (Part 1)
title_fullStr Local and regional anaesthesia in dogs and cats: Overview of concepts and drugs (Part 1)
title_full_unstemmed Local and regional anaesthesia in dogs and cats: Overview of concepts and drugs (Part 1)
title_short Local and regional anaesthesia in dogs and cats: Overview of concepts and drugs (Part 1)
title_sort local and regional anaesthesia in dogs and cats: overview of concepts and drugs (part 1)
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196681/
https://www.ncbi.nlm.nih.gov/pubmed/31965742
http://dx.doi.org/10.1002/vms3.219
work_keys_str_mv AT grubbtamara localandregionalanaesthesiaindogsandcatsoverviewofconceptsanddrugspart1
AT lobpriseheidi localandregionalanaesthesiaindogsandcatsoverviewofconceptsanddrugspart1