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PSGL-1 restricts HIV-1 infectivity by blocking virus particle attachment to target cells

P-selectin glycoprotein ligand-1 (PSGL-1) is a dimeric, mucin-like, 120-kDa glycoprotein that binds to P-, E-, and L-selectins. PSGL-1 is expressed primarily on the surface of lymphoid and myeloid cells and is up-regulated during inflammation to mediate leukocyte tethering and rolling on the surface...

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Detalles Bibliográficos
Autores principales:	Fu, Yajing, He, Sijia, Waheed, Abdul A., Dabbagh, Deemah, Zhou, Zheng, Trinité, Benjamin, Wang, Zhao, Yu, Jieshi, Wang, Dan, Li, Feng, Levy, David N., Shang, Hong, Freed, Eric O., Wu, Yuntao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2020
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196789/ https://www.ncbi.nlm.nih.gov/pubmed/32273392 http://dx.doi.org/10.1073/pnas.1916054117

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