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PSGL-1 restricts HIV-1 infectivity by blocking virus particle attachment to target cells

P-selectin glycoprotein ligand-1 (PSGL-1) is a dimeric, mucin-like, 120-kDa glycoprotein that binds to P-, E-, and L-selectins. PSGL-1 is expressed primarily on the surface of lymphoid and myeloid cells and is up-regulated during inflammation to mediate leukocyte tethering and rolling on the surface...

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Detalles Bibliográficos
Autores principales: Fu, Yajing, He, Sijia, Waheed, Abdul A., Dabbagh, Deemah, Zhou, Zheng, Trinité, Benjamin, Wang, Zhao, Yu, Jieshi, Wang, Dan, Li, Feng, Levy, David N., Shang, Hong, Freed, Eric O., Wu, Yuntao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196789/
https://www.ncbi.nlm.nih.gov/pubmed/32273392
http://dx.doi.org/10.1073/pnas.1916054117

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