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Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases
Yeast strains with low levels of the replicative DNA polymerases (alpha, delta, and epsilon) have high levels of chromosome deletions, duplications, and translocations. By examining the patterns of mutations induced in strains with low levels of DNA polymerase by the human protein APOBEC3B (a protei...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196835/ https://www.ncbi.nlm.nih.gov/pubmed/32277034 http://dx.doi.org/10.1073/pnas.1922472117 |