HNF1A recruits KDM6A to activate differentiated acinar cell programs that suppress pancreatic cancer

Defects in transcriptional regulators of pancreatic exocrine differentiation have been implicated in pancreatic tumorigenesis, but the molecular mechanisms are poorly understood. The locus encoding the transcription factor HNF1A harbors susceptibility variants for pancreatic ductal adenocarcinoma (P...

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Detalles Bibliográficos
Autores principales: Kalisz, Mark, Bernardo, Edgar, Beucher, Anthony, Maestro, Miguel Angel, del Pozo, Natalia, Millán, Irene, Haeberle, Lena, Schlensog, Martin, Safi, Sami Alexander, Knoefel, Wolfram Trudo, Grau, Vanessa, de Vas, Matías, Shpargel, Karl B, Vaquero, Eva, Magnuson, Terry, Ortega, Sagrario, Esposito, Irene, Real, Francisco X, Ferrer, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196917/
https://www.ncbi.nlm.nih.gov/pubmed/32154941
http://dx.doi.org/10.15252/embj.2019102808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196917/
https://www.ncbi.nlm.nih.gov/pubmed/32154941
http://dx.doi.org/10.15252/embj.2019102808

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