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Recent Progress on Lipid Intake and Chronic Kidney Disease

The incidence of chronic kidney disease (CKD) is associated with major abnormalities in circulating lipoproteins and renal lipid metabolism. This article elaborates on the mechanisms of CKD and lipid uptake abnormalities. The viewpoint we supported is that lipid abnormalities directly cause CKD, res...

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Detalles Bibliográficos
Autores principales: Pei, Ke, Gui, Ting, Li, Chao, Zhang, Qian, Feng, Huichao, Li, Yunlun, Wu, Jibiao, Gai, Zhibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196967/
https://www.ncbi.nlm.nih.gov/pubmed/32382547
http://dx.doi.org/10.1155/2020/3680397
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author Pei, Ke
Gui, Ting
Li, Chao
Zhang, Qian
Feng, Huichao
Li, Yunlun
Wu, Jibiao
Gai, Zhibo
author_facet Pei, Ke
Gui, Ting
Li, Chao
Zhang, Qian
Feng, Huichao
Li, Yunlun
Wu, Jibiao
Gai, Zhibo
author_sort Pei, Ke
collection PubMed
description The incidence of chronic kidney disease (CKD) is associated with major abnormalities in circulating lipoproteins and renal lipid metabolism. This article elaborates on the mechanisms of CKD and lipid uptake abnormalities. The viewpoint we supported is that lipid abnormalities directly cause CKD, resulting in forming a vicious cycle. On the theoretical and experiment fronts, this inference has been verified by elaborately elucidating the role of lipid intake and accumulation as well as their influences on CKD. Taken together, these findings suggest that further understanding of lipid metabolism in CKD may lead to novel therapeutic approaches.
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spelling pubmed-71969672020-05-07 Recent Progress on Lipid Intake and Chronic Kidney Disease Pei, Ke Gui, Ting Li, Chao Zhang, Qian Feng, Huichao Li, Yunlun Wu, Jibiao Gai, Zhibo Biomed Res Int Review Article The incidence of chronic kidney disease (CKD) is associated with major abnormalities in circulating lipoproteins and renal lipid metabolism. This article elaborates on the mechanisms of CKD and lipid uptake abnormalities. The viewpoint we supported is that lipid abnormalities directly cause CKD, resulting in forming a vicious cycle. On the theoretical and experiment fronts, this inference has been verified by elaborately elucidating the role of lipid intake and accumulation as well as their influences on CKD. Taken together, these findings suggest that further understanding of lipid metabolism in CKD may lead to novel therapeutic approaches. Hindawi 2020-04-24 /pmc/articles/PMC7196967/ /pubmed/32382547 http://dx.doi.org/10.1155/2020/3680397 Text en Copyright © 2020 Ke Pei et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Pei, Ke
Gui, Ting
Li, Chao
Zhang, Qian
Feng, Huichao
Li, Yunlun
Wu, Jibiao
Gai, Zhibo
Recent Progress on Lipid Intake and Chronic Kidney Disease
title Recent Progress on Lipid Intake and Chronic Kidney Disease
title_full Recent Progress on Lipid Intake and Chronic Kidney Disease
title_fullStr Recent Progress on Lipid Intake and Chronic Kidney Disease
title_full_unstemmed Recent Progress on Lipid Intake and Chronic Kidney Disease
title_short Recent Progress on Lipid Intake and Chronic Kidney Disease
title_sort recent progress on lipid intake and chronic kidney disease
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196967/
https://www.ncbi.nlm.nih.gov/pubmed/32382547
http://dx.doi.org/10.1155/2020/3680397
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