Mucinous Histology, BRCA1/2 Mutations, and Elevated Tumor Mutational Burden in Colorectal Cancer

Mucinous colorectal carcinomas (MC) constitute 10% of colorectal malignancies. Recently, an increased risk of colorectal cancer has been demonstrated in germline BRCA1/2 mutation carriers. Furthermore, BRCA1/2 germline mutation carriers have exhibited a higher-than-expected frequency of MC tumors. H...

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Detalles Bibliográficos
Autores principales: Harpaz, Noa, Gatt, Yair Eli, Granit, Roy Zvi, Fruchtman, Hila, Hubert, Ayala, Grinshpun, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196997/
https://www.ncbi.nlm.nih.gov/pubmed/32377194
http://dx.doi.org/10.1155/2020/6421205

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