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Parallel Generalized Suffix Tree Construction for Genomic Data
After a decade of digitization and technological advancements, we have an abundance of usable genomic data, which provide unique insights into our well-being. However, such datasets are large in volume, and retrieving meaningful information from them is often challenging. Hence, different indexing t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197101/ http://dx.doi.org/10.1007/978-3-030-42266-0_1 |
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author | Aziz, Md Momin Al Thulasiraman, Parimala Mohammed, Noman |
author_facet | Aziz, Md Momin Al Thulasiraman, Parimala Mohammed, Noman |
author_sort | Aziz, Md Momin Al |
collection | PubMed |
description | After a decade of digitization and technological advancements, we have an abundance of usable genomic data, which provide unique insights into our well-being. However, such datasets are large in volume, and retrieving meaningful information from them is often challenging. Hence, different indexing techniques and data structures have been proposed to handle such a massive scale of data. We utilize one such technique: Generalized Suffix Tree (GST). In this paper, we introduce an efficient parallel generalized suffix tree construction algorithm that is scalable for arbitrary genomic datasets. Our construction mechanism employs shared and distributed memory architecture collectively while not posing any fixed, prior memory requirement as it uses external memory (disks). Our experimental results show that our proposed architecture offers around 4-times speedup with respect to the sequential algorithm with only 16 parallel processors. The experiments on different datasets and parameters also exhibit the scalability of the execution time. In addition, we utilize different string queries and demonstrate their execution time on such tree structure, illustrating the efficacy and usability of GST for genomic data. |
format | Online Article Text |
id | pubmed-7197101 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
record_format | MEDLINE/PubMed |
spelling | pubmed-71971012020-05-04 Parallel Generalized Suffix Tree Construction for Genomic Data Aziz, Md Momin Al Thulasiraman, Parimala Mohammed, Noman Algorithms for Computational Biology Article After a decade of digitization and technological advancements, we have an abundance of usable genomic data, which provide unique insights into our well-being. However, such datasets are large in volume, and retrieving meaningful information from them is often challenging. Hence, different indexing techniques and data structures have been proposed to handle such a massive scale of data. We utilize one such technique: Generalized Suffix Tree (GST). In this paper, we introduce an efficient parallel generalized suffix tree construction algorithm that is scalable for arbitrary genomic datasets. Our construction mechanism employs shared and distributed memory architecture collectively while not posing any fixed, prior memory requirement as it uses external memory (disks). Our experimental results show that our proposed architecture offers around 4-times speedup with respect to the sequential algorithm with only 16 parallel processors. The experiments on different datasets and parameters also exhibit the scalability of the execution time. In addition, we utilize different string queries and demonstrate their execution time on such tree structure, illustrating the efficacy and usability of GST for genomic data. 2020-02-01 /pmc/articles/PMC7197101/ http://dx.doi.org/10.1007/978-3-030-42266-0_1 Text en © Springer Nature Switzerland AG 2020 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Article Aziz, Md Momin Al Thulasiraman, Parimala Mohammed, Noman Parallel Generalized Suffix Tree Construction for Genomic Data |
title | Parallel Generalized Suffix Tree Construction for Genomic Data |
title_full | Parallel Generalized Suffix Tree Construction for Genomic Data |
title_fullStr | Parallel Generalized Suffix Tree Construction for Genomic Data |
title_full_unstemmed | Parallel Generalized Suffix Tree Construction for Genomic Data |
title_short | Parallel Generalized Suffix Tree Construction for Genomic Data |
title_sort | parallel generalized suffix tree construction for genomic data |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197101/ http://dx.doi.org/10.1007/978-3-030-42266-0_1 |
work_keys_str_mv | AT azizmdmominal parallelgeneralizedsuffixtreeconstructionforgenomicdata AT thulasiramanparimala parallelgeneralizedsuffixtreeconstructionforgenomicdata AT mohammednoman parallelgeneralizedsuffixtreeconstructionforgenomicdata |