Cargando…

FAT4 silencing promotes epithelial-to-mesenchymal transition and invasion via regulation of YAP and β-catenin activity in ovarian cancer

BACKGROUND: The adhesion molecule, FAT4, has a tumor suppressor function with a critical role in the epithelial-to-mesenchymal-transition (EMT) and anti-malignant growth in several cancers. No study has investigated yet its role in epithelial ovarian cancer (EOC) progression. In the present study, w...

Descripción completa

Detalles Bibliográficos
Autores principales:	Malgundkar, Shika Hanif, Burney, Ikram, Al Moundhri, Mansour, Al Kalbani, Moza, Lakhtakia, Ritu, Okamoto, Aikou, Tamimi, Yahya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197128/ https://www.ncbi.nlm.nih.gov/pubmed/32366234 http://dx.doi.org/10.1186/s12885-020-06900-7

Ejemplares similares

Epigenetic Status of FBXW7 Gene and Its Role in Ovarian Cancer Pathogenesis
por: Al Hinai, Meerah, et al.
Publicado: (2023)

Exosomes as crucial emerging tools for intercellular communication with therapeutic potential in ovarian cancer
por: Malgundkar, Shika Hanif, et al.
Publicado: (2023)

Molecular genetics complexity impeding research progress in breast and ovarian cancers
por: Gupta, Ishita, et al.
Publicado: (2017)

Clinicopathological Features and Outcomes of Gastrointestinal Stromal Tumours in Oman: A multi-centre study
por: Al-Maqrashi, Zainab, et al.
Publicado: (2021)

For Whom the Bell Does Not Toll: The invisible saga of cancer caregivers
por: Lakhtakia, Ritu, et al.
Publicado: (2019)

Changing Trends of Breast Cancer Survival in Sultanate of Oman
por: Kumar, Shiyam, et al.
Publicado: (2011)

Outcomes of Women with Non-Metastatic Triple-Negative Breast Cancer in Oman: A single-centre experience
por: Kumar, Shiyam, et al.
Publicado: (2019)

Outcome of Omani Women with Breast Cancer-associated Brain Metastases Experience from a University Hospital
por: Zahid, Khawaja F., et al.
Publicado: (2019)

Predictors of Hypersensitivity Reactions to Platinum-Based Chemotherapy in a Tertiary Care Hospital in Oman: A case control study
por: Salman, Bushra, et al.
Publicado: (2023)

Hymenialdisine is Cytotoxic Against Cisplatin-Sensitive but Not Against Cisplatin-Resistant Cell Lines
por: Abdullah, Nada, et al.
Publicado: (2021)

Boswellic acid sensitizes gastric cancer cells to Cisplatin-induced apoptosis via p53-mediated pathway
por: Al-Bahlani, Shadia, et al.
Publicado: (2020)

Complications and Management of Totally Implantable Central Venous Access Ports in Cancer Patients at a University Hospital in Oman
por: D’Souza, Philomena C., et al.
Publicado: (2021)

Effects of maternal age, parity and pre-pregnancy body mass index on the glucose challenge test and gestational diabetes mellitus
por: Abu-Heija, Adel T., et al.
Publicado: (2017)

Addition of Gallic Acid Overcomes Resistance to Cisplatin in Ovarian Cancer Cell Lines
por: Al Balushi, Najwa, et al.
Publicado: (2022)

Micro-Ribonucleic Acid and Carcinogenesis: Breast Cancer as an Example
por: Al-Khanbashi, Manal, et al.
Publicado: (2015)

Malformin-A1 (MA1) Sensitizes Chemoresistant Ovarian Cancer Cells to Cisplatin-Induced Apoptosis
por: Abdullah, Nada, et al.
Publicado: (2021)

Effect of YAP1 silencing on esophageal cancer
por: Zhao, Jia, et al.
Publicado: (2016)

Role of α-Catenin and its mechanosensing properties in regulating Hippo/YAP-dependent tissue growth
por: Sarpal, Ritu, et al.
Publicado: (2019)

Association between Dietary and Lifestyle Indices and Colorectal Cancer in Oman: A Case-Control Study
por: Mafiana, Rose N, et al.
Publicado: (2018)

Papillary follicular variant thyroid cancer in a malignant struma ovarii: a report of a rare case
por: Elshafie, Omayma, et al.
Publicado: (2022)

Gestational Trophoblastic Disease at Sultan Qaboos University Hospital: Prevalence, Risk Factors, Histological Features, Sonographic Findings, and Outcomes
por: Al Riyami, Nihal, et al.
Publicado: (2019)

Rarest of the Rare Metastatic Tubulocystic Carcinoma of Kidney
por: Yousuf, Hira, et al.
Publicado: (2020)

Symptom Perceptions and Help-Seeking Behaviours of Omani Patients Diagnosed with Late-Stage Colorectal Cancer: A Qualitative Study
por: Al Suqri, Mahera, et al.
Publicado: (2021)

Extraosseous Ewing sarcoma of the vagina: a rare entity
por: Machado, Lovina, et al.
Publicado: (2013)

Hospital Prevalence of Colorectal Cancer among Colonoscopy Recipients Attending a Tertiary Hospital in Oman: A Cross-Sectional Study
por: Alsumait, Alanoud F., et al.
Publicado: (2020)

Hepatocellular Carcinoma in Oman: An analysis of 284 cases
por: Al-Naamani, Khalid, et al.
Publicado: (2020)

β-catenin-mediated YAP signaling promotes human glioma growth
por: Wang, Yan, et al.
Publicado: (2017)

Signet ring cell carcinoma of the rectal stump in a known ulcerative colitis patient
por: Nadaf, Asmanaz, et al.
Publicado: (2023)

Insulin-Like Growth Factor 1 Gene Polymorphism and Breast Cancer Risk Among Arab Omani Women: A Case-Control Study
por: Al-Ajmi, Kawthar, et al.
Publicado: (2012)

Virtual Microscopy in Undergraduate Pathology Education: An early transformative experience in clinical reasoning
por: Lakhtakia, Ritu
Publicado: (2021)

Impact of Metabolic Syndrome Diagnosis and Its Treatment on Survival of Colorectal Cancer Patients
por: Mafiana, Rose N., et al.
Publicado: (2019)

The Prognostic Significance of Whole Blood Global and Specific DNA Methylation Levels in Gastric Adenocarcinoma
por: Al-Moundhri, Mansour S., et al.
Publicado: (2010)

Mature cystic ovarian teratoma without intracystic fat: Case report with the “fat within the wall” sign
por: AlGhamdi, Maram, et al.
Publicado: (2020)

YAP promotes osteogenesis and suppresses adipogenic differentiation by regulating β-catenin signaling
por: Pan, Jin-Xiu, et al.
Publicado: (2018)

α-Catenin levels determine direction of YAP/TAZ response to autophagy perturbation
por: Pavel, Mariana, et al.
Publicado: (2021)

Irigenin inhibits glioblastoma progression through suppressing YAP/β-catenin signaling
por: Xu, Jiayun, et al.
Publicado: (2022)

YAP and β-catenin cooperate to drive H. pylori-induced gastric tumorigenesis
por: Li, Nianshuang, et al.
Publicado: (2023)

244. Predictors and Outcomes of Multi-Drug Resistant Gram-Negative Bacteremia in Patients with Solid Tumours
por: Varghese, George M, et al.
Publicado: (2023)

YAP silencing by RB1 mutation is essential for small-cell lung cancer metastasis
por: Wu, Zhengming, et al.
Publicado: (2023)

Health-Related Quality of Life, Functioning, and Physical Symptoms of Adult Omani Colorectal Cancer Survivors
por: Al-Shandudi, Maryam, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gs0v0qh6qqdhqg7ofpqqkllckn