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Telomere length heterogeneity in ALT cells is maintained by PML-dependent localization of the BTR complex to telomeres
Telomeres consist of TTAGGG repeats bound by protein complexes that serve to protect the natural end of linear chromosomes. Most cells maintain telomere repeat lengths by using the enzyme telomerase, although there are some cancer cells that use a telomerase-independent mechanism of telomere extensi...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197349/ https://www.ncbi.nlm.nih.gov/pubmed/32217664 http://dx.doi.org/10.1101/gad.333963.119 |