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Lactate induces PD-L1 in HRAS(G12V)-positive oropharyngeal squamous cell carcinoma

Intratumoral lactate production negatively correlates with survival and tumor clearance in the setting of human papillomavirus positive oropharyngeal squamous cell carcinoma (HPV-positive OPSCC). Robust anti-tumor immune activity is required for tumor clearance in human patients and animal models of...

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Detalles Bibliográficos
Autores principales: Verma, Alexander K., Messerli, Shanta M., Miskimins, W. Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197448/
https://www.ncbi.nlm.nih.gov/pubmed/32391119
http://dx.doi.org/10.18632/oncotarget.27348