Cargando…

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients

Clinical, epidemiological and experimental data identified the insulin-like growth factor-1 receptor (IGF1R) as a candidate therapeutic target in oncology. While this paradigm is based on well-established biological facts, including the potent anti-apoptotic and cell survival capabilities of the rec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sinai-Livne, Tali, Pasmanik-Chor, Metsada, Cohen, Zoya, Tsarfaty, Ilan, Werner, Haim, Berger, Raanan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197451/ https://www.ncbi.nlm.nih.gov/pubmed/32391121 http://dx.doi.org/10.18632/oncotarget.27566

Ejemplares similares

Systems Analysis of Insulin and IGF1 Receptors Networks in Breast Cancer Cells Identifies Commonalities and Divergences in Expression Patterns
por: Sarfstein, Rive, et al.
Publicado: (2020)

Genome-Wide Analyses Identify Filamin-A As a Novel Downstream Target for Insulin and IGF1 Action
por: Aizen, Daniel, et al.
Publicado: (2018)

Identification of BRCA1 As a Potential Biomarker for Insulin-Like Growth Factor-1 Receptor Targeted Therapy in Breast Cancer
por: Cohen-Sinai, Tali, et al.
Publicado: (2017)

Basic and clinical significance of IGF-I-induced signatures in cancer
por: Werner, Haim, et al.
Publicado: (2010)

MicroRNA 132-3p Is Upregulated in Laron Syndrome Patients and Controls Longevity Gene Expression
por: Yaron-Saminsky, Danielle, et al.
Publicado: (2021)

eIF4E and eIF4GI have distinct and differential imprints on multiple myeloma's proteome and signaling
por: Attar-Schneider, Oshrat, et al.
Publicado: (2015)

Intercellular transfer of small RNAs from astrocytes to lung tumor cells induces resistance to chemotherapy
por: Menachem, Assaf, et al.
Publicado: (2016)

Effects of IKAP/hELP1 Deficiency on Gene Expression in Differentiating Neuroblastoma Cells: Implications for Familial Dysautonomia
por: Cohen-Kupiec, Rachel, et al.
Publicado: (2011)

Vitamin D manipulates miR-181c, miR-20b and miR-15a in human umbilical vein endothelial cells exposed to a diabetic-like environment
por: Zitman-Gal, Tali, et al.
Publicado: (2014)

Hierarchical Partitioning of Metazoan Protein Conservation Profiles Provides New Functional Insights
por: Witztum, Jonathan, et al.
Publicado: (2014)

Genome-Wide Profiling of Laron Syndrome Patients Identifies Novel Cancer Protection Pathways
por: Werner, Haim, et al.
Publicado: (2019)

Simulation and visualization of multiple KEGG pathways using BioNSi
por: Yeheskel, Adva, et al.
Publicado: (2018)

De novo transcriptome characterization of Iris atropurpurea (the Royal Iris) and phylogenetic analysis of MADS-box and R2R3-MYB gene families
por: Bar-Lev, Yamit, et al.
Publicado: (2021)

Author Correction: De novo transcriptome characterization of Iris atropurpurea (the Royal Iris) and phylogenetic analysis of MADS-box and R2R3-MYB gene families
por: Bar-Lev, Yamit, et al.
Publicado: (2021)

MicroRNA profiling of pancreatic ductal adenocarcinoma (PDAC) reveals signature expression related to lymph node metastasis
por: Lemberger, Moran, et al.
Publicado: (2019)

Beta Palmitate Improves Bone Length and Quality during Catch-Up Growth in Young Rats
por: Bar-Maisels, Meytal, et al.
Publicado: (2017)

HeatMapViewer: interactive display of 2D data in biology
por: Yachdav, Guy, et al.
Publicado: (2014)

The IGF Hormonal Network in Endometrial Cancer: Functions, Regulation, and Targeting Approaches
por: Bruchim, Ilan, et al.
Publicado: (2014)

Differential gene expression and transport functionality in the bundle sheath versus mesophyll – a potential role in leaf mineral homeostasis
por: Wigoda, Noa, et al.
Publicado: (2017)

A Tumor Microenvironment-Driven Network Regulated by STAT3 and p65 Negatively Controls the Enrichment of Cancer Stem Cells in Human HR+/HER2− Breast Cancer
por: Ben-Yaakov, Hagar, et al.
Publicado: (2023)

Inhibition of ZEB1 expression induces redifferentiation of adult human β cells expanded in vitro
por: Sintov, Elad, et al.
Publicado: (2015)

The Uncovered Function of the Drosophila GBA1a-Encoded Protein
por: Cabasso, Or, et al.
Publicado: (2021)

Serine peptidases and increased amounts of soluble proteins contribute to heat priming of the plant pathogenic fungus Botrytis cinerea
por: Zhang, Mingzhe, et al.
Publicado: (2023)

Author Correction: Transcriptome profiling of mouse colonic eosinophils reveals a key role for eosinophils in the induction of s100a8 and s100a9 in mucosal healing
por: Reichman, Hadar, et al.
Publicado: (2018)

Transcriptome profiling of mouse colonic eosinophils reveals a key role for eosinophils in the induction of s100a8 and s100a9 in mucosal healing
por: Reichman , Hadar, et al.
Publicado: (2017)

Reduced culture temperature attenuates oxidative stress and inflammatory response facilitating expansion and differentiation of adipose-derived stem cells
por: Tirza, Gal, et al.
Publicado: (2020)

Risk gene-set and pathways in 22q11.2 deletion-related schizophrenia: a genealogical molecular approach
por: Michaelovsky, Elena, et al.
Publicado: (2019)

STAT3 isoforms differentially affect ACE2 expression: A potential target for COVID‐19 therapy
por: Shamir, Inbal, et al.
Publicado: (2020)

Mesenchymal Stem Cell-Derived Extracellular Vesicles as Proposed Therapy in a Rat Model of Cerebral Small Vessel Disease
por: Guy, Reut, et al.
Publicado: (2022)

Immune cell C/EBPβ deficiency is associated with hepatic mononuclear defects and spontaneous hepatitis but not steatohepatitis induced liver fibrosis
por: Moshkovits, Itay, et al.
Publicado: (2022)

Downregulation of Mir-31, Mir-155, and Mir-564 in Chronic Myeloid Leukemia Cells
por: Hershkovitz Rokah, Oshrat, et al.
Publicado: (2012)

Correction: Cardiac remodeling secondary to chronic volume overload is attenuated by a novel MMP9/2 blocking antibody
por: Cohen, Lena, et al.
Publicado: (2020)

Role of reactive oxygen species in the anticancer activity of botanicals: Comparing sensitivity profiles
por: Cohen, Zoya, et al.
Publicado: (2017)

R269C variant of ESR1: high prevalence and differential function in a subset of pancreatic cancers
por: Boldes, Tomer, et al.
Publicado: (2020)

Drosophila melanogaster Mutated in its GBA1b Ortholog Recapitulates Neuronopathic Gaucher Disease
por: Cabasso, Or, et al.
Publicado: (2019)

Autophagy is induced and modulated by cholesterol depletion through transcription of autophagy-related genes and attenuation of flux
por: Shapira, Keren E., et al.
Publicado: (2021)

Deconvolution of the epigenetic age discloses distinct inter-personal variability in epigenetic aging patterns
por: Shahal, Tamar, et al.
Publicado: (2022)

Oculopharyngeal muscular dystrophy mutations link the RNA‐binding protein HNRNPQ to autophagosome biogenesis
por: Ishtayeh, Hasan, et al.
Publicado: (2023)

Featured Cover
por: Ishtayeh, Hasan, et al.
Publicado: (2023)

Heterogeneity in the Metastatic Microenvironment: JunB-Expressing Microglia Cells as Potential Drivers of Melanoma Brain Metastasis Progression
por: Adir, Orit, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1rspbv3j0o9kjlgontdevrjeb8