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DnaJ-PKAc fusion induces liver inflammation in a zebrafish model of fibrolamellar carcinoma
Fibrolamellar carcinoma (FLC) is a rare liver cancer that affects adolescents and young adults. Genomic analysis of FLC has revealed a 400 kb deletion in chromosome 19 that leads to the chimeric transcript DNAJB1-PRKACA (DnaJ-PKAc), comprised of the first exon of heat shock protein 40 (DNAJB1) and e...
Autores principales: | de Oliveira, Sofia, Houseright, Ruth A., Korte, Benjamin G., Huttenlocher, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197716/ https://www.ncbi.nlm.nih.gov/pubmed/32102783 http://dx.doi.org/10.1242/dmm.042564 |
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