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Multiplexed Gene Expression Tuning with Orthogonal Synthetic Gene Circuits

[Image: see text] Understanding the individual and joint contribution of multiple protein levels toward a phenotype requires precise and tunable multigene expression control. Here we introduce a pair of mammalian synthetic gene circuits that linearly and orthogonally control the expression of two re...

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Detalles Bibliográficos
Autores principales: Szenk, Mariola, Yim, Terrence, Balázsi, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197936/
https://www.ncbi.nlm.nih.gov/pubmed/32167761
http://dx.doi.org/10.1021/acssynbio.9b00534

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