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Multiplexed Gene Expression Tuning with Orthogonal Synthetic Gene Circuits
[Image: see text] Understanding the individual and joint contribution of multiple protein levels toward a phenotype requires precise and tunable multigene expression control. Here we introduce a pair of mammalian synthetic gene circuits that linearly and orthogonally control the expression of two re...
Autores principales: | Szenk, Mariola, Yim, Terrence, Balázsi, Gábor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197936/ https://www.ncbi.nlm.nih.gov/pubmed/32167761 http://dx.doi.org/10.1021/acssynbio.9b00534 |
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