Cargando…

Roles of the mitochondrial replisome in mitochondrial DNA deletion formation

Mitochondrial DNA (mtDNA) deletions are a common cause of human mitochondrial diseases. Mutations in the genes encoding components of the mitochondrial replisome, such as DNA polymerase gamma (Pol γ) and the mtDNA helicase Twinkle, have been associated with the accumulation of such deletions and the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oliveira, Marcos T., Pontes, Carolina de Bovi, Ciesielski, Grzegorz L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Sociedade Brasileira de Genética 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7197994/ https://www.ncbi.nlm.nih.gov/pubmed/32141473 http://dx.doi.org/10.1590/1678-4685-GMB-2019-0069

Ejemplares similares

Physical and Functional Interaction of Mitochondrial Single-Stranded DNA-Binding Protein and the Catalytic Subunit of DNA Polymerase Gamma
por: Ciesielski, Grzegorz L., et al.
Publicado: (2021)

Oxidative DNA damage stalls the human mitochondrial replisome
por: Stojkovič, Gorazd, et al.
Publicado: (2016)

Evidence for a two membrane–spanning autonomous mitochondrial DNA replisome
por: Meeusen, Shelly, et al.
Publicado: (2003)

The accessory subunit B of DNA polymerase γ is required for mitochondrial replisome function
por: Farge, Géraldine, et al.
Publicado: (2007)

Mitochondrial DNA maintenance in Drosophila melanogaster
por: Rodrigues, Ana P.C., et al.
Publicado: (2022)

Mechanisms of replication and repair in mitochondrial DNA deletion formation
por: Fontana, Gabriele A, et al.
Publicado: (2020)

LRR1-mediated replisome disassembly promotes DNA replication by recycling replisome components
por: Fan, Yilin, et al.
Publicado: (2021)

The mitochondrial DNA polymerase gamma degrades linear DNA fragments precluding the formation of deletions
por: Nissanka, Nadee, et al.
Publicado: (2018)

Structural rearrangements in the mitochondrial genome of Drosophila melanogaster induced by elevated levels of the replicative DNA helicase
por: Ciesielski, Grzegorz L, et al.
Publicado: (2018)

T7 replisome directly overcomes DNA damage
por: Sun, Bo, et al.
Publicado: (2015)

Coordinated DNA Replication by the Bacteriophage T4 Replisome
por: Noble, Erin, et al.
Publicado: (2015)

The Initial Response of a Eukaryotic Replisome to DNA Damage
por: Taylor, Martin R.G., et al.
Publicado: (2018)

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis
por: Campbell, Graham R, et al.
Publicado: (2011)

The replisome guides nucleosome assembly during DNA replication
por: Zhang, Wenshuo, et al.
Publicado: (2020)

The Interplay of Cohesin and the Replisome at Processive and Stressed DNA Replication Forks
por: van Schie, Janne J. M., et al.
Publicado: (2021)

How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication
por: Yeeles, Joseph T.P., et al.
Publicado: (2017)

Plasmid hypermutation using a targeted artificial DNA replisome
por: Yi, Xiao, et al.
Publicado: (2021)

Secondary structure of the human mitochondrial genome affects formation of deletions
por: Shamanskiy, Victor, et al.
Publicado: (2023)

Mechanisms of eukaryotic replisome disassembly
por: Moreno, Sara Priego, et al.
Publicado: (2020)

Mitochondrial DNA deletions and depletion within paraspinal muscles
por: Campbell, G R, et al.
Publicado: (2013)

Mitochondrial DNA deletions are associated with non-B DNA conformations
por: Damas, Joana, et al.
Publicado: (2012)

Replicating animal mitochondrial DNA
por: McKinney, Emily A., et al.
Publicado: (2013)

Mitochondrial DNA deletions in muscle satellite cells: implications for therapies
por: Spendiff, Sally, et al.
Publicado: (2013)

Recycling of single-stranded DNA-binding protein by the bacterial replisome
por: Spenkelink, Lisanne M, et al.
Publicado: (2019)

The inner workings of replisome-dependent control of DNA damage tolerance
por: Zhang, Tianpeng, et al.
Publicado: (2022)

Mechanisms for Maintaining Eukaryotic Replisome Progression in the Presence of DNA Damage
por: Guilliam, Thomas A.
Publicado: (2021)

Observing protein dynamics during DNA-lesion bypass by the replisome
por: Wilkinson, Elise M., et al.
Publicado: (2022)

Direct visualization of translesion DNA synthesis polymerase IV at the replisome
por: Tuan, Pham Minh, et al.
Publicado: (2022)

Replisome loading reduces chromatin motion independent of DNA synthesis
por: Pabba, Maruthi Kumar, et al.
Publicado: (2023)

Altered skeletal muscle (mitochondrial) properties in patients with mitochondrial DNA single deletion myopathy
por: Gehrig, Saskia Maria, et al.
Publicado: (2016)

Mitochondrial Ophthalmoplegia Is Not Only due to mtDNA Deletions
por: Finsterer, Josef
Publicado: (2019)

Speed variations of bacterial replisomes
por: Bhat, Deepak, et al.
Publicado: (2022)

The Eukaryotic Mismatch Recognition Complexes Track with the Replisome during DNA Synthesis
por: Haye, Joanna E., et al.
Publicado: (2015)

Chimeric DNA byproducts in strand displacement amplification using the T7 replisome
por: Nye, Dillon B., et al.
Publicado: (2022)

How Pol α-primase is targeted to replisomes to prime eukaryotic DNA replication
por: Jones, Morgan L., et al.
Publicado: (2023)

Selective removal of deletion-bearing mitochondrial DNA in heteroplasmic Drosophila
por: Kandul, Nikolay P., et al.
Publicado: (2016)

Subcellular origin of mitochondrial DNA deletions in human skeletal muscle
por: Vincent, Amy E., et al.
Publicado: (2018)

Mitochondrial DNA exhibits resistance to induced point and deletion mutations
por: Valente, William J., et al.
Publicado: (2016)

Proteasome-dependent degradation of replisome components regulates faithful DNA replication
por: Roseaulin, Laura C, et al.
Publicado: (2013)

Thermodynamic analysis of DNA hybridization signatures near mitochondrial DNA deletion breakpoints
por: Lakshmanan, Lakshmi Narayanan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_5l4ppbrt15imh5psadvc585gmv