The combined risk effect among BIN1, CLU, and APOE genes in Alzheimer’s disease

Genome-wide associations studies (GWAS) are detecting new variants associated with late-onset of Alzheimer’s disease (LOAD), a multifactorial neurodegenerative disorder. The variants rs744373 BIN1, rs11136000 CLU and rs3764650 ABCA7 uncovered by GWAS led to different AD pathways, such as metabolism,...

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Detalles Bibliográficos
Autores principales: dos Santos, Lígia Ramos, Almeida, Jucimara Ferreira Figueiredo, Pimassoni, Lúcia Helena Sagrillo, Morelato, Renato Lírio, de Paula, Flavia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2020
Materias:
Human and Medical Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198034/
https://www.ncbi.nlm.nih.gov/pubmed/31469155
http://dx.doi.org/10.1590/1678-4685-GMB-2018-0320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198034/
https://www.ncbi.nlm.nih.gov/pubmed/31469155
http://dx.doi.org/10.1590/1678-4685-GMB-2018-0320

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