A Preliminary Report Showing Spinosad and Fluralaner Are Able to Incapacitate Cimex lectularius L., the Common Bed Bug

Cimex lectularius L., the common bed bug, is a hematophagous human ectoparasite. The veterinary drugs, spinosad and fluralaner, were studied for their ability to incapacitate C. lectularius when administered in a blood meal using an artificial feeding system under laboratory conditions. Tested drug...

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Detalles Bibliográficos
Autor principal: Sheele, Johnathan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Miscellaneous
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198093/
https://www.ncbi.nlm.nih.gov/pubmed/32377477
http://dx.doi.org/10.7759/cureus.7529
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author Sheele, Johnathan M
author_facet Sheele, Johnathan M
author_sort Sheele, Johnathan M
collection PubMed
description Cimex lectularius L., the common bed bug, is a hematophagous human ectoparasite. The veterinary drugs, spinosad and fluralaner, were studied for their ability to incapacitate C. lectularius when administered in a blood meal using an artificial feeding system under laboratory conditions. Tested drug doses were based on the reported peak blood levels in animals given the drugs. Spinosad at doses 1,000 ng/mL or higher resulted in 75% or greater bed bug incapacitation (defined as death or immobility). Fluralaner at doses 500 ng/mL or higher had 100% bed bug incapacitation. Both drugs were significantly more effective than controls at these doses (P < 0.001).
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spelling pubmed-71980932020-05-06 A Preliminary Report Showing Spinosad and Fluralaner Are Able to Incapacitate Cimex lectularius L., the Common Bed Bug Sheele, Johnathan M Cureus Miscellaneous Cimex lectularius L., the common bed bug, is a hematophagous human ectoparasite. The veterinary drugs, spinosad and fluralaner, were studied for their ability to incapacitate C. lectularius when administered in a blood meal using an artificial feeding system under laboratory conditions. Tested drug doses were based on the reported peak blood levels in animals given the drugs. Spinosad at doses 1,000 ng/mL or higher resulted in 75% or greater bed bug incapacitation (defined as death or immobility). Fluralaner at doses 500 ng/mL or higher had 100% bed bug incapacitation. Both drugs were significantly more effective than controls at these doses (P < 0.001). Cureus 2020-04-03 /pmc/articles/PMC7198093/ /pubmed/32377477 http://dx.doi.org/10.7759/cureus.7529 Text en Copyright © 2020, Sheele et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Miscellaneous
Sheele, Johnathan M
A Preliminary Report Showing Spinosad and Fluralaner Are Able to Incapacitate Cimex lectularius L., the Common Bed Bug
title A Preliminary Report Showing Spinosad and Fluralaner Are Able to Incapacitate Cimex lectularius L., the Common Bed Bug
title_full A Preliminary Report Showing Spinosad and Fluralaner Are Able to Incapacitate Cimex lectularius L., the Common Bed Bug
title_fullStr A Preliminary Report Showing Spinosad and Fluralaner Are Able to Incapacitate Cimex lectularius L., the Common Bed Bug
title_full_unstemmed A Preliminary Report Showing Spinosad and Fluralaner Are Able to Incapacitate Cimex lectularius L., the Common Bed Bug
title_short A Preliminary Report Showing Spinosad and Fluralaner Are Able to Incapacitate Cimex lectularius L., the Common Bed Bug
title_sort preliminary report showing spinosad and fluralaner are able to incapacitate cimex lectularius l., the common bed bug
topic Miscellaneous
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198093/
https://www.ncbi.nlm.nih.gov/pubmed/32377477
http://dx.doi.org/10.7759/cureus.7529
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