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High-resolution HLA phased haplotype frequencies to predict the success of unrelated donor searches and clinical outcome following hematopoietic stem cell transplantation

HLA matching is a critical factor for successful allogeneic hematopoietic stem cell transplantation. For unrelated donor searches, matching is usually based on high-resolution typing at five HLA loci, looking for a 10/10 match. Some studies have proposed that further matching at the haplotype level...

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Detalles Bibliográficos
Autores principales: Buhler, Stéphane, Baldomero, Helen, Ferrari-Lacraz, Sylvie, Nunes, José Manuel, Sanchez-Mazas, Alicia, Massouridi-Levrat, Stravroula, Heim, Dominik, Halter, Jörg, Nair, Gayathri, Chalandon, Yves, Schanz, Urs, Güngör, Tayfun, Nicoloso, Grazia, Tiercy, Jean-Marie, Passweg, Jakob, Villard, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198472/
https://www.ncbi.nlm.nih.gov/pubmed/30953025
http://dx.doi.org/10.1038/s41409-019-0520-6

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