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Invasion of Human Retinal Pigment Epithelial Cells by Porphyromonas gingivalis leading to Vacuolar/Cytosolic localization and Autophagy dysfunction In-Vitro

Recent epidemiological  studies link Periodontal disease(PD) to age-related macular degeneration (AMD). We documented earlier that Porphyromonas gingivalis(Pg), keystone oral-pathobiont, causative of PD, efficiently invades human gingival epithelial and blood-dendritic cells. Here, we investigated t...

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Detalles Bibliográficos
Autores principales: Arjunan, Pachiappan, Swaminathan, Radhika, Yuan, Jessie, Al-Shabrawey, Mohamed, Espinosa-Heidmann, Diego G., Nussbaum, Julian, Martin, Pamela M., Cutler, Christopher W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198524/
https://www.ncbi.nlm.nih.gov/pubmed/32366945
http://dx.doi.org/10.1038/s41598-020-64449-8