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Lithium response in bipolar disorder correlates with improved cell viability of patient derived cell lines

Lithium is an effective, well-established treatment for bipolar disorder (BD). However, the mechanisms of its action, and reasons for variations in clinical response, are unclear. We used neural precursor cells (NPCs) and lymphoblastoid cell lines (LCLs), from BD patients characterized for clinical...

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Detalles Bibliográficos
Autores principales: Paul, Pradip, Iyer, Shruti, Nadella, Ravi Kumar, Nayak, Rashmitha, Chellappa, Anirudh S., Ambardar, Sheetal, Sud, Reeteka, Sukumaran, Salil K., Purushottam, Meera, Jain, Sanjeev, Viswanath, Biju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198534/
https://www.ncbi.nlm.nih.gov/pubmed/32366893
http://dx.doi.org/10.1038/s41598-020-64202-1