Cargando…

TRAF3IP3 negatively regulates cytosolic RNA induced anti-viral signaling by promoting TBK1 K48 ubiquitination

Innate immunity to nucleic acids forms the backbone for anti-viral immunity and several inflammatory diseases. Upon sensing cytosolic viral RNA, retinoic acid-inducible gene-I-like receptors (RLRs) interact with the mitochondrial antiviral signaling protein (MAVS) and activate TANK-binding kinase 1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Deng, Meng, Tam, Jason W., Wang, Lufei, Liang, Kaixin, Li, Sirui, Zhang, Lu, Guo, Haitao, Luo, Xiaobo, Zhang, Yang, Petrucelli, Alex, Davis, Beckley K., Conti, Brian J., June Brickey, W., Ko, Ching-Chang, Lei, Yu L., Sun, Shaocong, Ting, Jenny P. -Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198545/ https://www.ncbi.nlm.nih.gov/pubmed/32366851 http://dx.doi.org/10.1038/s41467-020-16014-0

Ejemplares similares

TRAF7 negatively regulates the RLR signaling pathway by facilitating the K48-linked ubiquitination of TBK1
por: Huang, Jing-Ping, et al.
Publicado: (2023)

Targeting TRAF3IP2 inhibits angiogenesis in glioblastoma
por: Izadpanah, Amin, et al.
Publicado: (2022)

Inhibition of Antiviral Innate Immunity by Avibirnavirus VP3 via Blocking TBK1-TRAF3 Complex Formation and IRF3 Activation
por: Deng, Tingjuan, et al.
Publicado: (2021)

T cell development involves TRAF3IP3-mediated ERK signaling in the Golgi
por: Zou, Qiang, et al.
Publicado: (2015)

Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome
por: Yu, Xiaoyan, et al.
Publicado: (2018)

TRAF3IP3 promotes glioma progression through the ERK signaling pathway
por: Lin, Qi, et al.
Publicado: (2022)

TRAF3IP2, a novel therapeutic target in glioblastoma multiforme
por: Alt, Eckhard U., et al.
Publicado: (2018)

MAVS activates TBK1 and IKKε through TRAFs in NEMO dependent and independent manner
por: Fang, Run, et al.
Publicado: (2017)

Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis
por: Hüffmeier, Ulrike, et al.
Publicado: (2010)

TRAF3IP3 Is Cleaved by EV71 3C Protease and Exhibits Antiviral Activity
por: Li, Hui, et al.
Publicado: (2022)

FOSL1 Inhibits Type I Interferon Responses to Malaria and Viral Infections by Blocking TBK1 and TRAF3/TRIF Interactions
por: Cai, Baowei, et al.
Publicado: (2017)

Identification of human mutations in TRAF3IP1 in patients with nephronophthisis and retinal degeneration
por: Becker-Heck, A, et al.
Publicado: (2015)

Recruitment of TBK1 to cytosol‐invading Salmonella induces WIPI2‐dependent antibacterial autophagy
por: Thurston, Teresa LM, et al.
Publicado: (2016)

Common variants of ZNF750, RPTOR and TRAF3IP2 genes and psoriasis risk
por: Dębniak, T., et al.
Publicado: (2013)

TRAF3IP2–IL-17 Axis Strengthens the Gingival Defense against Pathogens
por: Zhang, J., et al.
Publicado: (2022)

Novel germline TRAF3IP3 mutation in a dyad with familial acute B lymphoblastic leukemia
por: Pommert, Lauren, et al.
Publicado: (2021)

SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex
por: Chen, Xiaojuan, et al.
Publicado: (2014)

MCPIP1 negatively regulate cellular antiviral innate immune responses through DUB and disruption of TRAF3-TBK1-IKKε complex
por: Chen, Xiaojuan, et al.
Publicado: (2018)

Swine Acute Diarrhea Syndrome Coronavirus Nucleocapsid Protein Antagonizes Interferon-β Production via Blocking the Interaction Between TRAF3 and TBK1
por: Zhou, Zhihai, et al.
Publicado: (2021)

TRAF5 and TRAF3IP2 Gene Polymorphisms Are Associated with Behçet's Disease and Vogt-Koyanagi-Harada Syndrome: A Case-Control Study
por: Xiang, Qin, et al.
Publicado: (2014)

Hippo signaling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade
por: Zhang, Qian, et al.
Publicado: (2017)

A TRAF-like motif of ICOS controls development of germinal center T follicular helper cells via TBK1
por: Pedros, Christophe, et al.
Publicado: (2016)

KRAP tethers IP(3) receptors to actin and licenses them to evoke cytosolic Ca(2+) signals
por: Thillaiappan, Nagendra Babu, et al.
Publicado: (2021)

The variants in PTPRB, TRAF3IP3, and DISC1 genes were associated with Graves’ disease in the Chinese population
por: Li, Wei, et al.
Publicado: (2022)

Knockdown of TRAF3IP2 suppresses the expression of VEGFA and the proliferation of keratinocytes and vascular endothelial cells
por: Song, Yali, et al.
Publicado: (2019)

NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes
por: Freeman, Leslie, et al.
Publicado: (2017)

Identification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization
por: Böhm, Beate, et al.
Publicado: (2012)

Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization
por: Bizet, Albane A., et al.
Publicado: (2015)

Clustering of IP(3) receptors by IP(3) retunes their regulation by IP(3) and Ca(2+)
por: Taufiq-Ur-Rahman,, et al.
Publicado: (2009)

Severe Acute Respiratory Syndrome Coronavirus M Protein Inhibits Type I Interferon Production by Impeding the Formation of TRAF3·TANK·TBK1/IKKϵ Complex
por: Siu, Kam-Leung, et al.
Publicado: (2009)

PPM1A silences cytosolic RNA sensing and antiviral defense through direct dephosphorylation of MAVS and TBK1
por: Xiang, Weiwen, et al.
Publicado: (2016)

Targeting TRAF3IP2, Compared to Rab27, is More Effective in Suppressing the Development and Metastasis of Breast Cancer
por: Alt, Eckhard U., et al.
Publicado: (2020)

TRAF3IP2 drives mesenchymal stem cell senescence via regulation of NAMPT-mediated NAD biosynthesis
por: Huang, Xiaoran, et al.
Publicado: (2023)

InsP(3)R-SEC5 interaction on phagosomes modulates innate immunity to Candida albicans by promoting cytosolic Ca(2+) elevation and TBK1 activity
por: Yang, Long, et al.
Publicado: (2018)

P22077 inhibits LPS-induced inflammatory response by promoting K48-linked ubiquitination and degradation of TRAF6
por: Zhao, Xi-Bao, et al.
Publicado: (2020)

C-Cbl negatively regulates TRAF6-mediated NF-κB activation by promoting K48-linked polyubiquitination of TRAF6
por: Jang, Hyun-Duk, et al.
Publicado: (2019)

Correction to: InsP(3)R-SEC5 interaction on phagosomes modulates innate immunity to Candida albicans by promoting cytosolic Ca (2+) elevation and TBK1 activity
por: Yang, Long, et al.
Publicado: (2020)

Astrocytic IP(3)Rs: Beyond IP(3)R2
por: Sherwood, Mark W., et al.
Publicado: (2021)

5mC and H3K9me3 of TRAF3IP2 promoter region accelerates the progression of translocation renal cell carcinoma
por: Yang, Lei, et al.
Publicado: (2022)

BICP0 Negatively Regulates TRAF6-Mediated NF-κB and Interferon Activation by Promoting K48-Linked Polyubiquitination of TRAF6
por: Cao, Chong, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_g8gq90t3p03an20kelb96h2ctr