Visualization of spatial and temporal temperature distributions with magnetic particle imaging for liver tumor ablation therapy

Temperature-resolved magnetic particle imaging (MPI) represents a promising tool for medical imaging applications. In this study an approach based on a single calibration measurement was applied for highlighting the potential of MPI for monitoring of temperatures during thermal ablation of liver tum...

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Autores principales: Salamon, J., Dieckhoff, J., Kaul, M. G., Jung, C., Adam, G., Möddel, M., Knopp, T., Draack, S., Ludwig, F., Ittrich, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198551/
https://www.ncbi.nlm.nih.gov/pubmed/32366912
http://dx.doi.org/10.1038/s41598-020-64280-1
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author Salamon, J.
Dieckhoff, J.
Kaul, M. G.
Jung, C.
Adam, G.
Möddel, M.
Knopp, T.
Draack, S.
Ludwig, F.
Ittrich, H.
author_facet Salamon, J.
Dieckhoff, J.
Kaul, M. G.
Jung, C.
Adam, G.
Möddel, M.
Knopp, T.
Draack, S.
Ludwig, F.
Ittrich, H.
author_sort Salamon, J.
collection PubMed
description Temperature-resolved magnetic particle imaging (MPI) represents a promising tool for medical imaging applications. In this study an approach based on a single calibration measurement was applied for highlighting the potential of MPI for monitoring of temperatures during thermal ablation of liver tumors. For this purpose, liver tissue and liver tumor phantoms embedding different superparamagnetic iron oxide nanoparticles (SPION) were prepared, locally heated up to 70 °C and recorded with MPI. Optimal temperature MPI SPIONs and a corresponding linear model for temperature calculation were determined. The temporal and spatial temperature distributions were compared with infrared (IR) camera results yielding quantitative agreements with a mean absolute deviation of 1 °C despite mismatches in boundary areas.
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spelling pubmed-71985512020-05-08 Visualization of spatial and temporal temperature distributions with magnetic particle imaging for liver tumor ablation therapy Salamon, J. Dieckhoff, J. Kaul, M. G. Jung, C. Adam, G. Möddel, M. Knopp, T. Draack, S. Ludwig, F. Ittrich, H. Sci Rep Article Temperature-resolved magnetic particle imaging (MPI) represents a promising tool for medical imaging applications. In this study an approach based on a single calibration measurement was applied for highlighting the potential of MPI for monitoring of temperatures during thermal ablation of liver tumors. For this purpose, liver tissue and liver tumor phantoms embedding different superparamagnetic iron oxide nanoparticles (SPION) were prepared, locally heated up to 70 °C and recorded with MPI. Optimal temperature MPI SPIONs and a corresponding linear model for temperature calculation were determined. The temporal and spatial temperature distributions were compared with infrared (IR) camera results yielding quantitative agreements with a mean absolute deviation of 1 °C despite mismatches in boundary areas. Nature Publishing Group UK 2020-05-04 /pmc/articles/PMC7198551/ /pubmed/32366912 http://dx.doi.org/10.1038/s41598-020-64280-1 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Salamon, J.
Dieckhoff, J.
Kaul, M. G.
Jung, C.
Adam, G.
Möddel, M.
Knopp, T.
Draack, S.
Ludwig, F.
Ittrich, H.
Visualization of spatial and temporal temperature distributions with magnetic particle imaging for liver tumor ablation therapy
title Visualization of spatial and temporal temperature distributions with magnetic particle imaging for liver tumor ablation therapy
title_full Visualization of spatial and temporal temperature distributions with magnetic particle imaging for liver tumor ablation therapy
title_fullStr Visualization of spatial and temporal temperature distributions with magnetic particle imaging for liver tumor ablation therapy
title_full_unstemmed Visualization of spatial and temporal temperature distributions with magnetic particle imaging for liver tumor ablation therapy
title_short Visualization of spatial and temporal temperature distributions with magnetic particle imaging for liver tumor ablation therapy
title_sort visualization of spatial and temporal temperature distributions with magnetic particle imaging for liver tumor ablation therapy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198551/
https://www.ncbi.nlm.nih.gov/pubmed/32366912
http://dx.doi.org/10.1038/s41598-020-64280-1
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