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Internalization mechanisms of brain-derived tau oligomers from patients with Alzheimer’s disease, progressive supranuclear palsy and dementia with Lewy bodies

Tau aggregates propagate in brain cells and transmit to neighboring cells as well as anatomically connected brain regions by prion-like mechanisms. Soluble tau aggregates (tau oligomers) are the most toxic species that initiate neurodegeneration in tauopathies, such as Alzheimer’s disease (AD), prog...

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Detalles Bibliográficos
Autores principales:	Puangmalai, Nicha, Bhatt, Nemil, Montalbano, Mauro, Sengupta, Urmi, Gaikwad, Sagar, Ventura, Frank, McAllen, Salome, Ellsworth, Anna, Garcia, Stephanie, Kayed, Rakez
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198578/ https://www.ncbi.nlm.nih.gov/pubmed/32366836 http://dx.doi.org/10.1038/s41419-020-2503-3

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