Reduction of depression-like behavior in rat model induced by ShRNA targeting norepinephrine transporter in locus coeruleus

Depression may be associated with reduced monoamine neurotransmission, particularly serotonin and norepinephrine (NE). Reuptake of NE by the norepinephrine transporter (NET) is the primary mechanism by which many of the antidepressants are high-affinity substrates for NET. This study aimed to examin...

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Detalles Bibliográficos
Autores principales: Du, Xiangdong, Yin, Ming, Yuan, Lian, Zhang, Guangya, Fan, Yan, Li, Zhe, Yuan, Nian, Lv, Xiaoli, Zhao, Xueli, Zou, Siyun, Deng, Wei, Kosten, Thomas R., Zhang, Xiang Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198598/
https://www.ncbi.nlm.nih.gov/pubmed/32366842
http://dx.doi.org/10.1038/s41398-020-0808-8

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