A PKB-SPEG signaling nexus links insulin resistance with diabetic cardiomyopathy by regulating calcium homeostasis

Diabetic cardiomyopathy is a progressive disease in diabetic patients, and myocardial insulin resistance contributes to its pathogenesis through incompletely-defined mechanisms. Striated muscle preferentially expressed protein kinase (SPEG) has two kinase-domains and is a critical cardiac regulator....

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Detalles Bibliográficos
Autores principales: Quan, Chao, Du, Qian, Li, Min, Wang, Ruizhen, Ouyang, Qian, Su, Shu, Zhu, Sangsang, Chen, Qiaoli, Sheng, Yang, Chen, Liang, Wang, Hong, Campbell, David G., MacKintosh, Carol, Yang, Zhongzhou, Ouyang, Kunfu, Wang, Hong Yu, Chen, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198626/
https://www.ncbi.nlm.nih.gov/pubmed/32367034
http://dx.doi.org/10.1038/s41467-020-16116-9

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