RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice

ABSTRACT: Progressive tubulointerstitial fibrosis is the common final outcome for all kidney diseases evolving into chronic kidney disease (CKD), whereas molecular mechanisms driving fibrogenesis remain elusive. Retinoic acid-inducible gene-I (RIG-I), an intracellular pattern recognition receptor, i...

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Detalles Bibliográficos
Autores principales: Zhou, Zhuanli, Ni, Jiayun, Li, Jingyao, Huo, Chuanbing, Miao, Naijun, Yin, Fan, Cheng, Qian, Xu, Dan, Xie, Hongyan, Chen, Panpan, Zheng, Peiqing, Zhang, Yingying, Zhou, Li, Zhang, Wei, Yu, Chen, Liu, Jun, Lu, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198651/
https://www.ncbi.nlm.nih.gov/pubmed/32036390
http://dx.doi.org/10.1007/s00109-020-01879-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198651/
https://www.ncbi.nlm.nih.gov/pubmed/32036390
http://dx.doi.org/10.1007/s00109-020-01879-x

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