Developmental Mutators and Early Onset Cancer

A new hypothesis suggests that somatic genome remodeling during normal development can cause mutations that explain many early onset cancers in children and adults.

Detalles Bibliográficos
Autores principales: Kentsis, Alex, Frank, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198762/
https://www.ncbi.nlm.nih.gov/pubmed/32411637
http://dx.doi.org/10.3389/fped.2020.00189
_version_ 1783529051639513088
author Kentsis, Alex
Frank, Steven A.
author_facet Kentsis, Alex
Frank, Steven A.
author_sort Kentsis, Alex
collection PubMed
description A new hypothesis suggests that somatic genome remodeling during normal development can cause mutations that explain many early onset cancers in children and adults.
format Online
Article
Text
id pubmed-7198762
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-71987622020-05-14 Developmental Mutators and Early Onset Cancer Kentsis, Alex Frank, Steven A. Front Pediatr Pediatrics A new hypothesis suggests that somatic genome remodeling during normal development can cause mutations that explain many early onset cancers in children and adults. Frontiers Media S.A. 2020-04-28 /pmc/articles/PMC7198762/ /pubmed/32411637 http://dx.doi.org/10.3389/fped.2020.00189 Text en Copyright © 2020 Kentsis and Frank. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Kentsis, Alex
Frank, Steven A.
Developmental Mutators and Early Onset Cancer
title Developmental Mutators and Early Onset Cancer
title_full Developmental Mutators and Early Onset Cancer
title_fullStr Developmental Mutators and Early Onset Cancer
title_full_unstemmed Developmental Mutators and Early Onset Cancer
title_short Developmental Mutators and Early Onset Cancer
title_sort developmental mutators and early onset cancer
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198762/
https://www.ncbi.nlm.nih.gov/pubmed/32411637
http://dx.doi.org/10.3389/fped.2020.00189
work_keys_str_mv AT kentsisalex developmentalmutatorsandearlyonsetcancer
AT frankstevena developmentalmutatorsandearlyonsetcancer

Ejemplares similares