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Tracking of an Oral Salmonella-Based Vaccine for Type 1 Diabetes in Non-obese Diabetic Mice
Type 1 diabetes (T1D) arises secondary to immune-driven destruction of pancreatic β-cells and manifests as insulin-deficient hyperglycemia. We showed that oral vaccination with live attenuated Salmonella, which simultaneously delivers autoantigens and a TGFβ expression vector to immune cells in the...
Autores principales: | Mbongue, Jacques C., Alhoshani, Ali, Rawson, Jeffrey, Garcia, Pablo A., Gonzalez, Nelson, Ferreri, Kevin, Kandeel, Fouad, Husseiny, Mohamed I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198770/ https://www.ncbi.nlm.nih.gov/pubmed/32411136 http://dx.doi.org/10.3389/fimmu.2020.00712 |
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