O-Acetylated Chemical Reporters of Glycosylation Can Display Metabolism-Dependent Background Labeling of Proteins but Are Generally Reliable Tools for the Identification of Glycoproteins

Monosaccharide analogs bearing bioorthogonal functionalities, or metabolic chemical reporters (MCRs) of glycosylation, have been used for approximately two decades for the visualization and identification of different glycoproteins. More recently, proteomics analyses have shown that per-O-acetylated...

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Detalles Bibliográficos
Autores principales: Darabedian, Narek, Yang, Bo, Ding, Richie, Cutolo, Giuliano, Zaro, Balyn W., Woo, Christina M., Pratt, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7198827/
https://www.ncbi.nlm.nih.gov/pubmed/32411667
http://dx.doi.org/10.3389/fchem.2020.00318

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