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Activation PDGFR-α/AKT Mediated Signaling Pathways in Oral Squamous Cell Carcinoma by Mesenchymal Stem/Stromal Cells Promotes Anti-apoptosis and Decreased Sensitivity to Cisplatin
Desmoplasia, a hallmark of a head and neck cancer, has both biologic and physiologic effects on cancer progression and chemotherapeutic response. Mesenchymal stem/stromal cells (MSCs), also known as mesenchymal stromal progenitor cells, have been shown to play a role in cancer progression, alter apo...
Autores principales: | Wang, Jia, Cui, Ruwen, Clement, Cecila G., Nawgiri, Ranjana, Powell, Don W., Pinchuk, Irina V., Watts, Tammara L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199219/ https://www.ncbi.nlm.nih.gov/pubmed/32411595 http://dx.doi.org/10.3389/fonc.2020.00552 |
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