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Thymic B Cells Promote Germinal Center-Like Structures and the Expansion of Follicular Helper T Cells in Lupus-Prone Mice
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the activation of autoreactive T and B cells, autoantibody production, and immune complex deposition in various organs. Previous evidence showed abnormal accumulation of B cells in the thymus of lupus-prone mice, but the ro...
Autores principales: | Hidalgo, Yessia, Núñez, Sarah, Fuenzalida, Maria Jose, Flores-Santibáñez, Felipe, Sáez, Pablo J., Dorner, Jessica, Lennon-Dumenil, Ana-Maria, Martínez, Victor, Zorn, Emmanuel, Rosemblatt, Mario, Sauma, Daniela, Bono, Maria Rosa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199236/ https://www.ncbi.nlm.nih.gov/pubmed/32411134 http://dx.doi.org/10.3389/fimmu.2020.00696 |
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