Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31

BACKGROUND: Genome-wide association studies (GWAS) have uncovered many genetic risk loci for psoriasis, yet many remain uncharacterised in terms of the causal gene and their biological mechanism in disease. This is largely a result of the findings that over 90% of GWAS variants map outside of protei...

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Detalles Bibliográficos
Autores principales: Ray-Jones, Helen, Duffus, Kate, McGovern, Amanda, Martin, Paul, Shi, Chenfu, Hankinson, Jenny, Gough, Oliver, Yarwood, Annie, Morris, Andrew P., Adamson, Antony, Taylor, Christopher, Ding, James, Gaddi, Vasanthi Priyadarshini, Fu, Yao, Gaffney, Patrick, Orozco, Gisela, Warren, Richard B., Eyre, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199343/
https://www.ncbi.nlm.nih.gov/pubmed/32366252
http://dx.doi.org/10.1186/s12915-020-00779-3

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