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Multiple-Hit Hypothesis in Parkinson’s Disease: LRRK2 and Inflammation
The multiple hit hypothesis for Parkinson’s disease (PD) suggests that an interaction between multiple (genetic and/or environmental) risk factors is needed to trigger the pathology. Leucine-Rich Repeat Kinase 2 (LRRK2) is an interesting protein to study in this context and is the focus of this revi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199384/ https://www.ncbi.nlm.nih.gov/pubmed/32410948 http://dx.doi.org/10.3389/fnins.2020.00376 |