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The Ratiometric Transcript Signature MX2/GPR183 Is Consistently Associated With RTS,S-Mediated Protection Against Controlled Human Malaria Infection

The RTS,S/AS01 vaccine provides partial protection against Plasmodium falciparum infection but determinants of protection and/or disease are unclear. Previously, anti-circumsporozoite protein (CSP) antibody titers and blood RNA signatures were associated with RTS,S/AS01 efficacy against controlled h...

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Detalles Bibliográficos
Autores principales:	Du, Ying, Thompson, Ethan G., Muller, Julius, Valvo, Joseph, Braun, Jackie, Shankar, Smitha, van den Berg, Robert A., Jongert, Erik, Dover, Drew, Sadoff, Jerald, Hendriks, Jenny, Gardner, Malcolm J., Ballou, W. Ripley, Regules, Jason A., van der Most, Robbert, Aderem, Alan, Ockenhouse, Christian F., Hill, Adrian V., Wille-Reece, Ulrike, Zak, Daniel E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199517/ https://www.ncbi.nlm.nih.gov/pubmed/32411130 http://dx.doi.org/10.3389/fimmu.2020.00669

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