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Sickle Cell Anemia Patients Display an Intricate Cellular and Serum Biomarker Network Highlighted by TCD4+CD69+ Lymphocytes, IL-17/MIP-1β, IL-12/VEGF, and IL-10/IP-10 Axis
BACKGROUND: Sickle cell anemia (SCA) is associated with a chronic proinflammatory state characterized by elevated leukocyte count, mortality from severe recurrent infections, and subsequent vasoocclusive complications with leukocyte adhesion to the endothelium and increased plasma levels of inflamma...
Autores principales: | Garcia, Nadja Pinto, Júnior, Alexander Leonardo S., Soares, Geyse Adriana S., Costa, Thainá Cristina C., dos Santos, Alicia Patrine C., Costa, Allyson Guimarães, Tarragô, Andréa Monteiro, Martins, Rejane Nina, do Carmo Leão Pontes, Flávia, de Almeida, Emerson Garcia, de Paula, Erich Vinícius, Martins-Filho, Olindo Assis, Malheiro, Adriana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199620/ https://www.ncbi.nlm.nih.gov/pubmed/32411797 http://dx.doi.org/10.1155/2020/4585704 |
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