Cargando…

Melatonin Ameliorates MI-Induced Cardiac Remodeling and Apoptosis through a JNK/p53-Dependent Mechanism in Diabetes Mellitus

Diabetes mellitus, a worldwide health threat, is considered an independent risk factor for cardiovascular diseases. The overall cardiovascular risk of diabetes is similar to the one having one myocardial infarction (MI) attack although the precise impact of diabetes on MI-induced myocardial anomalie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lu, Linhe, Ma, Jipeng, Sun, Mingming, Wang, Xiaowu, Gao, Erhe, Lu, Lintao, Ren, Jun, Yang, Lifang, Yang, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199622/ https://www.ncbi.nlm.nih.gov/pubmed/32411318 http://dx.doi.org/10.1155/2020/1535201

Ejemplares similares

Irisin attenuates myocardial ischemia/reperfusion‐induced cardiac dysfunction by regulating ER‐mitochondria interaction through a mitochondrial ubiquitin ligase‐dependent mechanism
por: Lu, Linhe, et al.
Publicado: (2020)

Electroacupuncture Pretreatment Mitigates Myocardial Ischemia/Reperfusion Injury via XBP1/GRP78/Akt Pathway
por: Wang, Nisha, et al.
Publicado: (2021)

Melatonin Restores Autophagic Flux by Activating the Sirt3/TFEB Signaling Pathway to Attenuate Doxorubicin-Induced Cardiomyopathy
por: Ma, Yanyan, et al.
Publicado: (2023)

Melatonin ameliorates hypoglycemic stress‐induced brain endothelial tight junction injury by inhibiting protein nitration of TP53‐induced glycolysis and apoptosis regulator
por: Wang, Cheng‐kun, et al.
Publicado: (2017)

Oxidative stress-induced apoptosis in granulosa cells involves JNK, p53 and Puma
por: Yang, Hongyan, et al.
Publicado: (2017)

Cardiac‐specific Mst1 deficiency inhibits ROS‐mediated JNK signalling to alleviate Ang II‐induced cardiomyocyte apoptosis
por: Cheng, Zheng, et al.
Publicado: (2018)

FSTL1-USP10-Notch1 Signaling Axis Protects Against Cardiac Dysfunction Through Inhibition of Myocardial Fibrosis in Diabetic Mice
por: Lu, Linhe, et al.
Publicado: (2021)

Paeoniflorin ameliorates cognitive impairment in Parkinson’s disease via JNK/p53 signaling
por: He, Zhu-qing, et al.
Publicado: (2022)

Ginsenoside Rh1 Alleviates HK-2 Apoptosis by Inhibiting ROS and the JNK/p53 Pathways
por: Yang, Qi, et al.
Publicado: (2020)

DHA ameliorates MeHg-induced PC12 cell apoptosis by inhibiting the ROS/JNK signaling pathway
por: Zhang, Hong, et al.
Publicado: (2021)

Actin remodeling mediates ROS production and JNK activation to drive apoptosis-induced proliferation
por: Farrell, Luchi, et al.
Publicado: (2022)

Melatonin-Mediated Suppression of mtROS-JNK-FOXO1 Pathway Alleviates Hypoxia-Induced Apoptosis in Porcine Granulosa Cells
por: Zhang, Xuan, et al.
Publicado: (2023)

The Ameliorative Effect of JNK Inhibitor D-JNKI-1 on Neomycin-Induced Apoptosis in HEI-OC1 Cells
por: Zhao, Junling, et al.
Publicado: (2022)

Melatonin-Medicated Neural JNK3 Up-Regulation Promotes Ameloblastic Mineralization
por: Ren, Qianhui, et al.
Publicado: (2021)

Melatonin Ameliorates Coxsackievirus B3-Induced Myocarditis by Regulating Apoptosis and Autophagy
por: Sang, Yimiao, et al.
Publicado: (2018)

Ethyl Acetate Fraction of Hedyotis diffusa Willd Induces Apoptosis via JNK/Nur77 Pathway in Hepatocellular Carcinoma Cells
por: Ning, Weimin, et al.
Publicado: (2022)

JNK inhibitor IX restrains pancreatic cancer through p53 and p21
por: Shi, Jingwei, et al.
Publicado: (2022)

Nobiletin ameliorates cardiac impairment and alleviates cardiac remodeling after acute myocardial infarction in rats via JNK regulation
por: Liu, Zumei, et al.
Publicado: (2021)

Melatonin ameliorates lung cell inflammation and apoptosis caused by Klebsiella pneumoniae via AMP-activated protein kinase
por: Jiang, Wei, et al.
Publicado: (2022)

ROS-dependent activation of JNK converts p53 into an efficient inhibitor of oncogenes leading to robust apoptosis
por: Shi, Y, et al.
Publicado: (2014)

HO-3867 Induces Apoptosis via the JNK Signaling Pathway in Human Osteosarcoma Cells
por: Lu, Peace Wun-Ang, et al.
Publicado: (2022)

He's Yangchao Recipe Ameliorates Ovarian Oxidative Stress of Aging Mice under Consecutive Superovulation Involving JNK- And P53-Related Mechanism
por: Zhao, Ying, et al.
Publicado: (2022)

Protective Effects of Astaxanthin on ConA-Induced Autoimmune Hepatitis by the JNK/p-JNK Pathway-Mediated Inhibition of Autophagy and Apoptosis
por: Li, Jingjing, et al.
Publicado: (2015)

JNK2 regulates vascular remodeling in pulmonary hypertension
por: Das, Mita, et al.
Publicado: (2018)

JNK inhibitor alleviates apoptosis of fetal neural stem cells induced by emulsified isoflurane
por: Zhou, Lei, et al.
Publicado: (2017)

Melatonin ameliorates intervertebral disc degeneration via the potential mechanisms of mitophagy induction and apoptosis inhibition
por: Chen, Yu, et al.
Publicado: (2019)

FUT2 Facilitates Autophagy and Suppresses Apoptosis via p53 and JNK Signaling in Lung Adenocarcinoma Cells
por: Zhang, Yuqi, et al.
Publicado: (2022)

Exosomes Derived from Mesenchymal Stem Cells Protect the Myocardium Against Ischemia/Reperfusion Injury Through Inhibiting Pyroptosis
por: Tang, Jiayou, et al.
Publicado: (2020)

Melatonin promotes gut anti-oxidative status in perinatal rat by remodeling the gut microbiome
por: Yi, Xudong, et al.
Publicado: (2023)

ANXA3 Silencing Ameliorates Intracranial Aneurysm via Inhibition of the JNK Signaling Pathway
por: Wang, Yang, et al.
Publicado: (2019)

Melatonin ameliorates myocardial injury by reducing apoptosis and autophagy of cardiomyocytes in a rat cardiopulmonary bypass model
por: Huang, Xiaolin, et al.
Publicado: (2021)

JNK regulates muscle remodeling via myostatin/SMAD inhibition
por: Lessard, Sarah J., et al.
Publicado: (2018)

Melatonin ameliorates the adverse effects of leptin on sperm
por: Almabhouh, Fayez A, et al.
Publicado: (2017)

Ninjinyoeito ameliorated cigarette smoke extract-induced apoptosis and inflammation through JNK signaling inhibition in human lung fibroblasts
por: Murata, Kenta, et al.
Publicado: (2022)

OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases
por: Wu, Wei, et al.
Publicado: (2019)

Novel MDM2 inhibitor SAR405838 (MI-773) induces p53-mediated apoptosis in neuroblastoma
por: Lu, Jiaxiong, et al.
Publicado: (2016)

Momordica charantia extracts ameliorate insulin resistance by regulating the expression of SOCS-3 and JNK in type 2 diabetes mellitus rats
por: Ma, Chunyu, et al.
Publicado: (2017)

Ganoderma lucidum polysaccharide ameliorated diabetes mellitus-induced erectile dysfunction in rats by regulating fibrosis and the NOS/ERK/JNK pathway
por: Yao, Xiaolin, et al.
Publicado: (2022)

Apoptosis of Bone Marrow Mesenchymal Stem Cells Caused by Homocysteine via Activating JNK Signal
por: Cai, Benzhi, et al.
Publicado: (2013)

SGLT1 Inhibition Attenuates Apoptosis in Diabetic Cardiomyopathy via the JNK and p38 Pathway
por: Lin, Na, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_8sfrge4lbavu9c158to7beud86