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Population Pharmacokinetics and Pharmacodynamics Modeling of Torasemide and Furosemide After Oral Repeated Administration in Healthy Dogs

Torasemide is a loop diuretic licensed in dogs for cardiogenic pulmonary oedema. The aim of this pharmacokinetic-pharmacodynamic (PK/PD) study was to define an optimally effective dosage regimen based on preclinical data. In a first study, 5 dogs received once-daily oral torasemide (0, 0.1, 0.2, 0.4...

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Detalles Bibliográficos
Autores principales:	Pelligand, Ludovic, Guillot, Emilie, Geneteau, Anne, Guyonnet, Jerome, Magnier, Reynald, Elliott, Jonathan, Peyrou, Mathieu, Jacobs, Matthieu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Veterinary Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199743/ https://www.ncbi.nlm.nih.gov/pubmed/32411731 http://dx.doi.org/10.3389/fvets.2020.00151

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