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Sequences of Reverse Transcribed Brain DNA Are Modified by Learning

Brain metabolic DNA (BMD) is continuously synthesized by reverse transcription in presynaptic synaptosomes and astroglia, and is partly transferred to nuclei after acquiring the double stranded configuration. Synthesis and turnover of BMD are markedly dependent on brain activity, as shown by circadi...

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Detalles Bibliográficos
Autores principales: Giuditta, Antonio, Casalino, Joyce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199793/
https://www.ncbi.nlm.nih.gov/pubmed/32410960
http://dx.doi.org/10.3389/fnmol.2020.00057