Cargando…

Recurrence Rate in a Patient Treated with Colon Resection Followed by Chemotherapy in Comparison to a Patient Treated with Colon Resection without Chemotherapy

Given that colon cancer is one of the most prevalent cancers worldwide, it is essential to employ strategies to try to reduce its incidence and recurrence rate. Though colon cancer is a sporadic disease in the vast majority of cases, multiple risk factors are linked to this disease, namely, obesity...

Descripción completa

Detalles Bibliográficos
Autores principales: Alshehri, Khalid A, Altuwaylie, Talal M, Fakieha, Abdulaziz, AlGhamdi, Ghassan, Alshahrani, Saad M, Mikwar, Zaher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199900/
https://www.ncbi.nlm.nih.gov/pubmed/32377492
http://dx.doi.org/10.7759/cureus.7544
_version_ 1783529231147335680
author Alshehri, Khalid A
Altuwaylie, Talal M
Fakieha, Abdulaziz
AlGhamdi, Ghassan
Alshahrani, Saad M
Mikwar, Zaher
author_facet Alshehri, Khalid A
Altuwaylie, Talal M
Fakieha, Abdulaziz
AlGhamdi, Ghassan
Alshahrani, Saad M
Mikwar, Zaher
author_sort Alshehri, Khalid A
collection PubMed
description Given that colon cancer is one of the most prevalent cancers worldwide, it is essential to employ strategies to try to reduce its incidence and recurrence rate. Though colon cancer is a sporadic disease in the vast majority of cases, multiple risk factors are linked to this disease, namely, obesity and cigarette smoking. Additionally, not many studies have been done in Saudi Arabia studying the recurrence rate of colon cancer. Therefore, we conducted a retrospective cohort study at King Khalid Hospital, King Abdulaziz Medical City, National Guard Health Affairs (NGHA), Jeddah, Saudi Arabia to investigate the recurrence rate of colon cancer in patients treated with complete colon resection followed by chemotherapy versus patients treated with colon resection alone via electronic and paper medical records. A total of 120 patients were included in this study; 61 were males (50.8%) and 59 were females (49.2%). According to our findings, the recurrence rate in patients who underwent surgical resection with adjuvant chemotherapy was 15.6% (n = 10), while the recurrence rate in patients with surgery alone was 21.4% (n = 12). Cancer recurrence is associated with significant morbidity and mortality. Therefore, further studies should be done to investigate the recurrence rate in patients with risk factors to identify and deal with the causes of recurrence.
format Online
Article
Text
id pubmed-7199900
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-71999002020-05-06 Recurrence Rate in a Patient Treated with Colon Resection Followed by Chemotherapy in Comparison to a Patient Treated with Colon Resection without Chemotherapy Alshehri, Khalid A Altuwaylie, Talal M Fakieha, Abdulaziz AlGhamdi, Ghassan Alshahrani, Saad M Mikwar, Zaher Cureus Gastroenterology Given that colon cancer is one of the most prevalent cancers worldwide, it is essential to employ strategies to try to reduce its incidence and recurrence rate. Though colon cancer is a sporadic disease in the vast majority of cases, multiple risk factors are linked to this disease, namely, obesity and cigarette smoking. Additionally, not many studies have been done in Saudi Arabia studying the recurrence rate of colon cancer. Therefore, we conducted a retrospective cohort study at King Khalid Hospital, King Abdulaziz Medical City, National Guard Health Affairs (NGHA), Jeddah, Saudi Arabia to investigate the recurrence rate of colon cancer in patients treated with complete colon resection followed by chemotherapy versus patients treated with colon resection alone via electronic and paper medical records. A total of 120 patients were included in this study; 61 were males (50.8%) and 59 were females (49.2%). According to our findings, the recurrence rate in patients who underwent surgical resection with adjuvant chemotherapy was 15.6% (n = 10), while the recurrence rate in patients with surgery alone was 21.4% (n = 12). Cancer recurrence is associated with significant morbidity and mortality. Therefore, further studies should be done to investigate the recurrence rate in patients with risk factors to identify and deal with the causes of recurrence. Cureus 2020-04-04 /pmc/articles/PMC7199900/ /pubmed/32377492 http://dx.doi.org/10.7759/cureus.7544 Text en Copyright © 2020, Alshehri et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Gastroenterology
Alshehri, Khalid A
Altuwaylie, Talal M
Fakieha, Abdulaziz
AlGhamdi, Ghassan
Alshahrani, Saad M
Mikwar, Zaher
Recurrence Rate in a Patient Treated with Colon Resection Followed by Chemotherapy in Comparison to a Patient Treated with Colon Resection without Chemotherapy
title Recurrence Rate in a Patient Treated with Colon Resection Followed by Chemotherapy in Comparison to a Patient Treated with Colon Resection without Chemotherapy
title_full Recurrence Rate in a Patient Treated with Colon Resection Followed by Chemotherapy in Comparison to a Patient Treated with Colon Resection without Chemotherapy
title_fullStr Recurrence Rate in a Patient Treated with Colon Resection Followed by Chemotherapy in Comparison to a Patient Treated with Colon Resection without Chemotherapy
title_full_unstemmed Recurrence Rate in a Patient Treated with Colon Resection Followed by Chemotherapy in Comparison to a Patient Treated with Colon Resection without Chemotherapy
title_short Recurrence Rate in a Patient Treated with Colon Resection Followed by Chemotherapy in Comparison to a Patient Treated with Colon Resection without Chemotherapy
title_sort recurrence rate in a patient treated with colon resection followed by chemotherapy in comparison to a patient treated with colon resection without chemotherapy
topic Gastroenterology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199900/
https://www.ncbi.nlm.nih.gov/pubmed/32377492
http://dx.doi.org/10.7759/cureus.7544
work_keys_str_mv AT alshehrikhalida recurrencerateinapatienttreatedwithcolonresectionfollowedbychemotherapyincomparisontoapatienttreatedwithcolonresectionwithoutchemotherapy
AT altuwaylietalalm recurrencerateinapatienttreatedwithcolonresectionfollowedbychemotherapyincomparisontoapatienttreatedwithcolonresectionwithoutchemotherapy
AT fakiehaabdulaziz recurrencerateinapatienttreatedwithcolonresectionfollowedbychemotherapyincomparisontoapatienttreatedwithcolonresectionwithoutchemotherapy
AT alghamdighassan recurrencerateinapatienttreatedwithcolonresectionfollowedbychemotherapyincomparisontoapatienttreatedwithcolonresectionwithoutchemotherapy
AT alshahranisaadm recurrencerateinapatienttreatedwithcolonresectionfollowedbychemotherapyincomparisontoapatienttreatedwithcolonresectionwithoutchemotherapy
AT mikwarzaher recurrencerateinapatienttreatedwithcolonresectionfollowedbychemotherapyincomparisontoapatienttreatedwithcolonresectionwithoutchemotherapy