STK11 and KEAP1 mutations as prognostic biomarkers in an observational real-world lung adenocarcinoma cohort

INTRODUCTION: Somatic mutations in STK11 and KEAP1, frequently comutated in non-squamous non-small cell lung cancer (NSQ NSCLC), have been associated with poor response to immune checkpoint blockade (ICB). However, previous reports lack non-ICB controls needed to properly ascertain the predictive na...

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Detalles Bibliográficos
Autores principales: Papillon-Cavanagh, Simon, Doshi, Parul, Dobrin, Radu, Szustakowski, Joseph, Walsh, Alice M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199918/
https://www.ncbi.nlm.nih.gov/pubmed/32312757
http://dx.doi.org/10.1136/esmoopen-2020-000706

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7199918/
https://www.ncbi.nlm.nih.gov/pubmed/32312757
http://dx.doi.org/10.1136/esmoopen-2020-000706

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