The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection

Antibiotics are widely used in the treatment of bacterial infections. Although known for their microbicidal activity, antibiotics may also interfere with the host’s immune system. Here, we analyzed the effects of bedaquiline (BDQ), an inhibitor of the mycobacterial ATP synthase, on human macrophages...

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Detalles Bibliográficos
Autores principales: Giraud-Gatineau, Alexandre, Coya, Juan Manuel, Maure, Alexandra, Biton, Anne, Thomson, Michael, Bernard, Elliott M, Marrec, Jade, Gutierrez, Maximiliano G, Larrouy-Maumus, Gérald, Brosch, Roland, Gicquel, Brigitte, Tailleux, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200153/
https://www.ncbi.nlm.nih.gov/pubmed/32369020
http://dx.doi.org/10.7554/eLife.55692

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