Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation

A highly aggressive subset of pancreatic ductal adenocarcinomas undergo trans-differentiation into the squamous lineage during disease progression. Here, we investigated whether squamous trans-differentiation of human and mouse pancreatic cancer cells can influence the phenotype of non-neoplastic ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Somerville, Tim DD, Biffi, Giulia, Daßler-Plenker, Juliane, Hur, Stella K, He, Xue-Yan, Vance, Krysten E, Miyabayashi, Koji, Xu, Yali, Maia-Silva, Diogo, Klingbeil, Olaf, Demerdash, Osama E, Preall, Jonathan B, Hollingsworth, Michael A, Egeblad, Mikala, Tuveson, David A, Vakoc, Christopher R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200154/
https://www.ncbi.nlm.nih.gov/pubmed/32329713
http://dx.doi.org/10.7554/eLife.53381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200154/
https://www.ncbi.nlm.nih.gov/pubmed/32329713
http://dx.doi.org/10.7554/eLife.53381

Ejemplares similares