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mRNA decapping is an evolutionarily conserved modulator of neuroendocrine signaling that controls development and ageing

Eukaryotic 5’−3’ mRNA decay plays important roles during development and in response to stress, regulating gene expression post-transcriptionally. In Caenorhabditis elegans, deficiency of DCAP-1/DCP1, the essential co-factor of the major cytoplasmic mRNA decapping enzyme, impacts normal development,...

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Detalles Bibliográficos
Autores principales: Borbolis, Fivos, Rallis, John, Kanatouris, George, Kokla, Nikolitsa, Karamalegkos, Antonis, Vasileiou, Christina, Vakaloglou, Katerina M, Diallinas, George, Stravopodis, Dimitrios J, Zervas, Christos G, Syntichaki, Popi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200159/
https://www.ncbi.nlm.nih.gov/pubmed/32366357
http://dx.doi.org/10.7554/eLife.53757