Rifabutin corneal deposits localized to the deep stroma using anterior segment optical coherence tomography

PURPOSE: To demonstrate that rifabutin-related corneal deposits are localized to the deep stroma using anterior segment optical coherence tomography (OCT) and confocal microscopy. OBSERVATIONS: A 55-year-old male with a history of human immunodeficiency virus (HIV) and disseminated mycobacterium avi...

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Detalles Bibliográficos
Autores principales: Zhang, Tianyi, Sun, Catherine Q., Lin, Yijie B., Schallhorn, Julie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200216/
https://www.ncbi.nlm.nih.gov/pubmed/32382686
http://dx.doi.org/10.1016/j.ajoc.2020.100701
Descripción
Sumario:PURPOSE: To demonstrate that rifabutin-related corneal deposits are localized to the deep stroma using anterior segment optical coherence tomography (OCT) and confocal microscopy. OBSERVATIONS: A 55-year-old male with a history of human immunodeficiency virus (HIV) and disseminated mycobacterium avium complex on rifabutin treatment for 3 years presented with bilateral corneal deposits. Confocal microscopy and anterior segment OCT confirm that rifabutin-related corneal deposits are located in the deep stroma, rather than in the endothelium. CONCLUSIONS: And Importance: Rifabutin deposits localize to the deep corneal stroma, and can be seen with both confocal microscopy and anterior segment OCT. Anterior segment OCT is a widely available and easily used diagnostic tool, and can provide utility in the diagnosis of corneal deposits.

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