Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications

Curcumin, a yellow-colored polyphenol extracted from the rhizome of turmeric root, is commonly used as a spice and nutritional supplement. It exhibits many pharmacological activities such as anti-inflammatory, anti-bacterial, anti-cancer, anti-Alzheimer, and anti-fungal. However, the therapeutic app...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Lu, Yao, Lee, Robert J, Xiang, Guangya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200256/
https://www.ncbi.nlm.nih.gov/pubmed/32431504
http://dx.doi.org/10.2147/IJN.S210320
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author Chen, Yan
Lu, Yao
Lee, Robert J
Xiang, Guangya
author_facet Chen, Yan
Lu, Yao
Lee, Robert J
Xiang, Guangya
author_sort Chen, Yan
collection PubMed
description Curcumin, a yellow-colored polyphenol extracted from the rhizome of turmeric root, is commonly used as a spice and nutritional supplement. It exhibits many pharmacological activities such as anti-inflammatory, anti-bacterial, anti-cancer, anti-Alzheimer, and anti-fungal. However, the therapeutic application of curcumin is limited by its extremely low solubility in aqueous buffer, instability in body fluids, and rapid metabolism. Nano delivery system has shown excellent potential to improve the solubility, biocompatibility and therapeutic effect of curcumin. In this review, we focus on the recent development of nano encapsulated curcumin and its potential for biomedical applications.
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spelling pubmed-72002562020-05-19 Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications Chen, Yan Lu, Yao Lee, Robert J Xiang, Guangya Int J Nanomedicine Review Curcumin, a yellow-colored polyphenol extracted from the rhizome of turmeric root, is commonly used as a spice and nutritional supplement. It exhibits many pharmacological activities such as anti-inflammatory, anti-bacterial, anti-cancer, anti-Alzheimer, and anti-fungal. However, the therapeutic application of curcumin is limited by its extremely low solubility in aqueous buffer, instability in body fluids, and rapid metabolism. Nano delivery system has shown excellent potential to improve the solubility, biocompatibility and therapeutic effect of curcumin. In this review, we focus on the recent development of nano encapsulated curcumin and its potential for biomedical applications. Dove 2020-05-01 /pmc/articles/PMC7200256/ /pubmed/32431504 http://dx.doi.org/10.2147/IJN.S210320 Text en © 2020 Chen et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Chen, Yan
Lu, Yao
Lee, Robert J
Xiang, Guangya
Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications
title Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications
title_full Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications
title_fullStr Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications
title_full_unstemmed Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications
title_short Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications
title_sort nano encapsulated curcumin: and its potential for biomedical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200256/
https://www.ncbi.nlm.nih.gov/pubmed/32431504
http://dx.doi.org/10.2147/IJN.S210320
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