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A Small-Molecule Wnt Mimic Improves Human Limbal Stem Cell Ex Vivo Expansion

Ex vivo cultured limbal stem/progenitor cells is an effective alternative to other surgical treatments for limbal stem cell deficiency, but a standard xenobiotic-free method for culturing the LSCs in vitro needs to be optimized. Because Wnt ligands are required for LSC expansion and preservation in ...

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Detalles Bibliográficos
Autores principales: Zhang, Chi, Mei, Hua, Robertson, Sarah Y.T., Lee, Ho-Jin, Deng, Sophie X., Zheng, Jie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7200314/
https://www.ncbi.nlm.nih.gov/pubmed/32361505
http://dx.doi.org/10.1016/j.isci.2020.101075